Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BG60_19620Pyrimidine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)    
Predicted Functional Partners:
BG60_29850
3,4-dihydroxy-2-butanone 4-phosphate synthase; Bifunctional enzyme DHBP synthase/GTP cyclohydrolase II-like protein; functions in riboflavin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.984
BG60_29835
Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.921
BG60_14130
3,4-dihydroxy-2-butanone 4-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.777
BG60_31100
Guanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.766
BG60_03680
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.741
BG60_35785
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.741
BG60_01590
Extradiol dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.733
eno
Enolase; Catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.732
BG60_29830
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.672
BG60_26615
Riboflavin synthase subunit beta; RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the ribo [...]
  
 
 0.645
Your Current Organism:
Caballeronia zhejiangensis
NCBI taxonomy Id: 871203
Other names: Burkholderia sp. OP-1, Burkholderia zhejiangensis, C. zhejiangensis, CCTCC AB 2010354, Caballeronia zhejiangensis (Lu et al. 2012) Dobritsa and Samadpour 2016, DSM 28073, KCTC 23300, LMG 27258, LMG:27258, Paraburkholderia zhejiangensis, Paraburkholderia zhejiangensis (Lu et al. 2012) Sawana et al. 2015, strain OP-1
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