Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
BG60_24410Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa)    
Predicted Functional Partners:
BG60_30230
Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.976
BG60_16490
Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.901
BG60_04495
ferredoxin-NADP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.884
BG60_32130
Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.860
BG60_32375
Fur family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.822
BG60_05650
Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.818
BG60_11570
Phosphoadenosine phosphosulfate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.803
rho
Transcription termination factor Rho; An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.802
putA
Transcriptional regulator; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.780
groEL
Molecular chaperone GroEL; 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth; Derived by a [...]
   
 
 0.777
Your Current Organism:
Caballeronia zhejiangensis
NCBI taxonomy Id: 871203
Other names: Burkholderia sp. OP-1, Burkholderia zhejiangensis, C. zhejiangensis, CCTCC AB 2010354, Caballeronia zhejiangensis (Lu et al. 2012) Dobritsa and Samadpour 2016, DSM 28073, KCTC 23300, LMG 27258, LMG:27258, Paraburkholderia zhejiangensis, Paraburkholderia zhejiangensis (Lu et al. 2012) Sawana et al. 2015, strain OP-1
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