| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFM45135.1 | EFM47304.1 | HMPREF0580_2306 | HMPREF0580_0044 | DoxX family protein; Pfam: PF07681. | Transglycosylase-like domain protein; Pfam: PF03990,PF07501,PF06737; InterPro: IPR011098. | 0.510 |
| EFM46047.1 | EFM47304.1 | HMPREF0580_1369 | HMPREF0580_0044 | ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003439. | Transglycosylase-like domain protein; Pfam: PF03990,PF07501,PF06737; InterPro: IPR011098. | 0.624 |
| EFM46047.1 | ispE | HMPREF0580_1369 | HMPREF0580_0042 | ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003439. | Putative 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.451 |
| EFM46047.1 | ksgA | HMPREF0580_1369 | HMPREF0580_0043 | ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003439. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.661 |
| EFM46047.1 | metG | HMPREF0580_1369 | HMPREF0580_0046 | ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003439. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.438 |
| EFM46275.1 | EFM47304.1 | HMPREF0580_1045 | HMPREF0580_0044 | Hypothetical protein. | Transglycosylase-like domain protein; Pfam: PF03990,PF07501,PF06737; InterPro: IPR011098. | 0.470 |
| EFM46275.1 | ntcA | HMPREF0580_1045 | HMPREF0580_0382 | Hypothetical protein. | Cyclic nucleotide-binding domain protein; COG: COG0664; Pfam: PF00027; InterPro: IPR014710. | 0.517 |
| EFM47304.1 | EFM45135.1 | HMPREF0580_0044 | HMPREF0580_2306 | Transglycosylase-like domain protein; Pfam: PF03990,PF07501,PF06737; InterPro: IPR011098. | DoxX family protein; Pfam: PF07681. | 0.510 |
| EFM47304.1 | EFM46047.1 | HMPREF0580_0044 | HMPREF0580_1369 | Transglycosylase-like domain protein; Pfam: PF03990,PF07501,PF06737; InterPro: IPR011098. | ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003439. | 0.624 |
| EFM47304.1 | EFM46275.1 | HMPREF0580_0044 | HMPREF0580_1045 | Transglycosylase-like domain protein; Pfam: PF03990,PF07501,PF06737; InterPro: IPR011098. | Hypothetical protein. | 0.470 |
| EFM47304.1 | EFM47305.1 | HMPREF0580_0044 | HMPREF0580_0045 | Transglycosylase-like domain protein; Pfam: PF03990,PF07501,PF06737; InterPro: IPR011098. | Hydrolase, TatD family; COG: COG0084; Pfam: PF01026; InterPro: IPR001130. | 0.832 |
| EFM47304.1 | EFM47307.1 | HMPREF0580_0044 | HMPREF0580_0047 | Transglycosylase-like domain protein; Pfam: PF03990,PF07501,PF06737; InterPro: IPR011098. | Dolichyl-phosphate-mannose-protein mannosyltransferase; COG: COG1928; Pfam: PF02366. | 0.613 |
| EFM47304.1 | ispE | HMPREF0580_0044 | HMPREF0580_0042 | Transglycosylase-like domain protein; Pfam: PF03990,PF07501,PF06737; InterPro: IPR011098. | Putative 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.891 |
| EFM47304.1 | ksgA | HMPREF0580_0044 | HMPREF0580_0043 | Transglycosylase-like domain protein; Pfam: PF03990,PF07501,PF06737; InterPro: IPR011098. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.973 |
| EFM47304.1 | metG | HMPREF0580_0044 | HMPREF0580_0046 | Transglycosylase-like domain protein; Pfam: PF03990,PF07501,PF06737; InterPro: IPR011098. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.575 |
| EFM47304.1 | ntcA | HMPREF0580_0044 | HMPREF0580_0382 | Transglycosylase-like domain protein; Pfam: PF03990,PF07501,PF06737; InterPro: IPR011098. | Cyclic nucleotide-binding domain protein; COG: COG0664; Pfam: PF00027; InterPro: IPR014710. | 0.570 |
| EFM47304.1 | rsmI | HMPREF0580_0044 | HMPREF0580_0048 | Transglycosylase-like domain protein; Pfam: PF03990,PF07501,PF06737; InterPro: IPR011098. | S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.527 |
| EFM47305.1 | EFM47304.1 | HMPREF0580_0045 | HMPREF0580_0044 | Hydrolase, TatD family; COG: COG0084; Pfam: PF01026; InterPro: IPR001130. | Transglycosylase-like domain protein; Pfam: PF03990,PF07501,PF06737; InterPro: IPR011098. | 0.832 |
| EFM47305.1 | EFM47307.1 | HMPREF0580_0045 | HMPREF0580_0047 | Hydrolase, TatD family; COG: COG0084; Pfam: PF01026; InterPro: IPR001130. | Dolichyl-phosphate-mannose-protein mannosyltransferase; COG: COG1928; Pfam: PF02366. | 0.635 |
| EFM47305.1 | ispE | HMPREF0580_0045 | HMPREF0580_0042 | Hydrolase, TatD family; COG: COG0084; Pfam: PF01026; InterPro: IPR001130. | Putative 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.817 |