| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fur | ideR | HMPREF0580_1277 | HMPREF0580_0068 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367. | 0.772 |
| fur | oxyR | HMPREF0580_1277 | HMPREF0580_1672 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | 0.430 |
| fur | rpoB | HMPREF0580_1277 | HMPREF0580_0660 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.889 |
| fur | rpoD | HMPREF0580_1277 | HMPREF0580_1616 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.931 |
| fur | tpx | HMPREF0580_1277 | HMPREF0580_1351 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | Redoxin family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.522 |
| galE | ideR | HMPREF0580_0264 | HMPREF0580_0068 | UDP-glucose 4-epimerase; COG: COG1087; Pfam: PF01370; InterPro: IPR005886. | Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367. | 0.595 |
| galE | rpoD | HMPREF0580_0264 | HMPREF0580_1616 | UDP-glucose 4-epimerase; COG: COG1087; Pfam: PF01370; InterPro: IPR005886. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.453 |
| hemA | ideR | HMPREF0580_0348 | HMPREF0580_0068 | glutamyl-tRNAGlu reductase domain protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367. | 0.580 |
| ideR | fur | HMPREF0580_0068 | HMPREF0580_1277 | Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367. | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | 0.772 |
| ideR | galE | HMPREF0580_0068 | HMPREF0580_0264 | Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367. | UDP-glucose 4-epimerase; COG: COG1087; Pfam: PF01370; InterPro: IPR005886. | 0.595 |
| ideR | hemA | HMPREF0580_0068 | HMPREF0580_0348 | Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367. | glutamyl-tRNAGlu reductase domain protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.580 |
| ideR | metN | HMPREF0580_0068 | HMPREF0580_0251 | Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367. | ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. | 0.849 |
| ideR | mntH | HMPREF0580_0068 | HMPREF0580_1142 | Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367. | Metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family; COG: COG1914; Pfam: PF01566; InterPro: IPR001046. | 0.553 |
| ideR | oxyR | HMPREF0580_0068 | HMPREF0580_1672 | Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367. | LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | 0.572 |
| ideR | rpoB | HMPREF0580_0068 | HMPREF0580_0660 | Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.565 |
| ideR | rpoD | HMPREF0580_0068 | HMPREF0580_1616 | Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.567 |
| ideR | serC | HMPREF0580_0068 | HMPREF0580_0069 | Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367. | Putative phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.789 |
| ideR | tpx | HMPREF0580_0068 | HMPREF0580_1351 | Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367. | Redoxin family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.551 |
| metN | ideR | HMPREF0580_0251 | HMPREF0580_0068 | ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. | Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367. | 0.849 |
| mntH | ideR | HMPREF0580_1142 | HMPREF0580_0068 | Metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family; COG: COG1914; Pfam: PF01566; InterPro: IPR001046. | Iron dependent repressor DNA binding domain protein; COG: COG1321; Pfam: PF01325,PF02742; InterPro: IPR001367. | 0.553 |