| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFM46033.1 | ung | HMPREF0580_1355 | HMPREF0580_0093 | RNA methyltransferase, RsmD family; COG: COG0742; Pfam: PF03602; InterPro: IPR004398. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.450 |
| EFM46811.1 | polA | HMPREF0580_0529 | HMPREF0580_1480 | Hypothetical protein. | DNA-directed DNA polymerase; COG: COG0749; Pfam: PF02739,PF01367,PF00476; InterPro: IPR002298. | 0.502 |
| EFM46811.1 | ung | HMPREF0580_0529 | HMPREF0580_0093 | Hypothetical protein. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.602 |
| EFM46811.1 | xthA | HMPREF0580_0529 | HMPREF0580_0097 | Hypothetical protein. | Putative exodeoxyribonuclease III; COG: COG0708; Pfam: PF03372; InterPro: IPR004808. | 0.907 |
| EFM46811.1 | xthA3 | HMPREF0580_0529 | HMPREF0580_1939 | Hypothetical protein. | Putative exodeoxyribonuclease III; COG: COG0708; Pfam: PF03372; InterPro: IPR004808. | 0.907 |
| EFM47232.1 | groL | HMPREF0580_0092 | HMPREF0580_0091 | Hypothetical protein. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.649 |
| EFM47232.1 | ung | HMPREF0580_0092 | HMPREF0580_0093 | Hypothetical protein. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.728 |
| dnaN | polA | HMPREF0580_0321 | HMPREF0580_1480 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; COG: COG0749; Pfam: PF02739,PF01367,PF00476; InterPro: IPR002298. | 0.999 |
| dnaN | ung | HMPREF0580_0321 | HMPREF0580_0093 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.875 |
| dnaN | xthA | HMPREF0580_0321 | HMPREF0580_0097 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative exodeoxyribonuclease III; COG: COG0708; Pfam: PF03372; InterPro: IPR004808. | 0.931 |
| dnaN | xthA3 | HMPREF0580_0321 | HMPREF0580_1939 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative exodeoxyribonuclease III; COG: COG0708; Pfam: PF03372; InterPro: IPR004808. | 0.931 |
| groL | EFM47232.1 | HMPREF0580_0091 | HMPREF0580_0092 | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Hypothetical protein. | 0.649 |
| groL | polA | HMPREF0580_0091 | HMPREF0580_1480 | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | DNA-directed DNA polymerase; COG: COG0749; Pfam: PF02739,PF01367,PF00476; InterPro: IPR002298. | 0.632 |
| groL | ung | HMPREF0580_0091 | HMPREF0580_0093 | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.512 |
| pepN | polA | HMPREF0580_2047 | HMPREF0580_1480 | Membrane alanyl aminopeptidase; COG: COG0308; Pfam: PF01433; InterPro: IPR012778. | DNA-directed DNA polymerase; COG: COG0749; Pfam: PF02739,PF01367,PF00476; InterPro: IPR002298. | 0.429 |
| pepN | ung | HMPREF0580_2047 | HMPREF0580_0093 | Membrane alanyl aminopeptidase; COG: COG0308; Pfam: PF01433; InterPro: IPR012778. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.564 |
| polA | EFM46811.1 | HMPREF0580_1480 | HMPREF0580_0529 | DNA-directed DNA polymerase; COG: COG0749; Pfam: PF02739,PF01367,PF00476; InterPro: IPR002298. | Hypothetical protein. | 0.502 |
| polA | dnaN | HMPREF0580_1480 | HMPREF0580_0321 | DNA-directed DNA polymerase; COG: COG0749; Pfam: PF02739,PF01367,PF00476; InterPro: IPR002298. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.999 |
| polA | groL | HMPREF0580_1480 | HMPREF0580_0091 | DNA-directed DNA polymerase; COG: COG0749; Pfam: PF02739,PF01367,PF00476; InterPro: IPR002298. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.632 |
| polA | pepN | HMPREF0580_1480 | HMPREF0580_2047 | DNA-directed DNA polymerase; COG: COG0749; Pfam: PF02739,PF01367,PF00476; InterPro: IPR002298. | Membrane alanyl aminopeptidase; COG: COG0308; Pfam: PF01433; InterPro: IPR012778. | 0.429 |