| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFM46586.1 | EFM47274.1 | HMPREF0580_0768 | HMPREF0580_0014 | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | Dihydroxyacetone kinase, phosphotransfer subunit; Pfam: PF03610,PF00381; InterPro: IPR012844. | 0.946 |
| EFM46586.1 | eno | HMPREF0580_0768 | HMPREF0580_0033 | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.763 |
| EFM46586.1 | fbaA | HMPREF0580_0768 | HMPREF0580_0100 | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.946 |
| EFM46586.1 | gap | HMPREF0580_0768 | HMPREF0580_1374 | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.709 |
| EFM46586.1 | gpm | HMPREF0580_0768 | HMPREF0580_0545 | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.923 |
| EFM46586.1 | pgi | HMPREF0580_0768 | HMPREF0580_2133 | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.967 |
| EFM46586.1 | pgk | HMPREF0580_0768 | HMPREF0580_1375 | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | Phosphoglycerate kinase; COG: COG0126; Pfam: PF00162; InterPro: IPR001576; Belongs to the phosphoglycerate kinase family. | 0.703 |
| EFM46586.1 | pyk | HMPREF0580_0768 | HMPREF0580_0241 | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697; Belongs to the pyruvate kinase family. | 0.979 |
| EFM46586.1 | tkt | HMPREF0580_0768 | HMPREF0580_1391 | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | Transketolase; COG: COG0021; Pfam: PF00456,PF02779,PF02780; InterPro: IPR005478; Belongs to the transketolase family. | 0.878 |
| EFM46586.1 | tpiA | HMPREF0580_0768 | HMPREF0580_1376 | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.742 |
| EFM47274.1 | EFM46586.1 | HMPREF0580_0014 | HMPREF0580_0768 | Dihydroxyacetone kinase, phosphotransfer subunit; Pfam: PF03610,PF00381; InterPro: IPR012844. | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | 0.946 |
| EFM47274.1 | eno | HMPREF0580_0014 | HMPREF0580_0033 | Dihydroxyacetone kinase, phosphotransfer subunit; Pfam: PF03610,PF00381; InterPro: IPR012844. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.884 |
| EFM47274.1 | fbaA | HMPREF0580_0014 | HMPREF0580_0100 | Dihydroxyacetone kinase, phosphotransfer subunit; Pfam: PF03610,PF00381; InterPro: IPR012844. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.931 |
| EFM47274.1 | gap | HMPREF0580_0014 | HMPREF0580_1374 | Dihydroxyacetone kinase, phosphotransfer subunit; Pfam: PF03610,PF00381; InterPro: IPR012844. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.727 |
| EFM47274.1 | gpm | HMPREF0580_0014 | HMPREF0580_0545 | Dihydroxyacetone kinase, phosphotransfer subunit; Pfam: PF03610,PF00381; InterPro: IPR012844. | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.438 |
| EFM47274.1 | pgi | HMPREF0580_0014 | HMPREF0580_2133 | Dihydroxyacetone kinase, phosphotransfer subunit; Pfam: PF03610,PF00381; InterPro: IPR012844. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.969 |
| EFM47274.1 | pgk | HMPREF0580_0014 | HMPREF0580_1375 | Dihydroxyacetone kinase, phosphotransfer subunit; Pfam: PF03610,PF00381; InterPro: IPR012844. | Phosphoglycerate kinase; COG: COG0126; Pfam: PF00162; InterPro: IPR001576; Belongs to the phosphoglycerate kinase family. | 0.834 |
| EFM47274.1 | pyk | HMPREF0580_0014 | HMPREF0580_0241 | Dihydroxyacetone kinase, phosphotransfer subunit; Pfam: PF03610,PF00381; InterPro: IPR012844. | Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697; Belongs to the pyruvate kinase family. | 0.868 |
| EFM47274.1 | tkt | HMPREF0580_0014 | HMPREF0580_1391 | Dihydroxyacetone kinase, phosphotransfer subunit; Pfam: PF03610,PF00381; InterPro: IPR012844. | Transketolase; COG: COG0021; Pfam: PF00456,PF02779,PF02780; InterPro: IPR005478; Belongs to the transketolase family. | 0.953 |
| EFM47274.1 | tpiA | HMPREF0580_0014 | HMPREF0580_1376 | Dihydroxyacetone kinase, phosphotransfer subunit; Pfam: PF03610,PF00381; InterPro: IPR012844. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.788 |