| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFM46586.1 | actP | HMPREF0580_0768 | HMPREF0580_0367 | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | 0.678 |
| EFM46586.1 | copA | HMPREF0580_0768 | HMPREF0580_0366 | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | Heavy metal-associated domain protein; Pfam: PF00403. | 0.441 |
| EFM46586.1 | hemB | HMPREF0580_0768 | HMPREF0580_0362 | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | Porphobilinogen synthase; COG: COG0113; Pfam: PF00490; InterPro: IPR013785; Belongs to the ALAD family. | 0.449 |
| EFM46586.1 | purB | HMPREF0580_0768 | HMPREF0580_0365 | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | Lyase; COG: COG0015; Pfam: PF00206,PF08328; InterPro: IPR000362. | 0.947 |
| actP | EFM46586.1 | HMPREF0580_0367 | HMPREF0580_0768 | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | 0.678 |
| actP | copA | HMPREF0580_0367 | HMPREF0580_0366 | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | Heavy metal-associated domain protein; Pfam: PF00403. | 0.987 |
| actP | hemB | HMPREF0580_0367 | HMPREF0580_0362 | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | Porphobilinogen synthase; COG: COG0113; Pfam: PF00490; InterPro: IPR013785; Belongs to the ALAD family. | 0.591 |
| actP | hemL | HMPREF0580_0367 | HMPREF0580_0364 | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | Glutamate-1-semialdehyde-2,1-aminomutase; COG: COG0001; Pfam: PF00202; InterPro: IPR004639. | 0.577 |
| actP | purB | HMPREF0580_0367 | HMPREF0580_0365 | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | Lyase; COG: COG0015; Pfam: PF00206,PF08328; InterPro: IPR000362. | 0.732 |
| actP | rplN | HMPREF0580_0367 | HMPREF0580_2243 | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.562 |
| copA | EFM46586.1 | HMPREF0580_0366 | HMPREF0580_0768 | Heavy metal-associated domain protein; Pfam: PF00403. | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | 0.441 |
| copA | actP | HMPREF0580_0366 | HMPREF0580_0367 | Heavy metal-associated domain protein; Pfam: PF00403. | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | 0.987 |
| copA | hemB | HMPREF0580_0366 | HMPREF0580_0362 | Heavy metal-associated domain protein; Pfam: PF00403. | Porphobilinogen synthase; COG: COG0113; Pfam: PF00490; InterPro: IPR013785; Belongs to the ALAD family. | 0.415 |
| copA | hemL | HMPREF0580_0366 | HMPREF0580_0364 | Heavy metal-associated domain protein; Pfam: PF00403. | Glutamate-1-semialdehyde-2,1-aminomutase; COG: COG0001; Pfam: PF00202; InterPro: IPR004639. | 0.492 |
| copA | purB | HMPREF0580_0366 | HMPREF0580_0365 | Heavy metal-associated domain protein; Pfam: PF00403. | Lyase; COG: COG0015; Pfam: PF00206,PF08328; InterPro: IPR000362. | 0.707 |
| copA | rplN | HMPREF0580_0366 | HMPREF0580_2243 | Heavy metal-associated domain protein; Pfam: PF00403. | Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.562 |
| hemB | EFM46586.1 | HMPREF0580_0362 | HMPREF0580_0768 | Porphobilinogen synthase; COG: COG0113; Pfam: PF00490; InterPro: IPR013785; Belongs to the ALAD family. | Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869. | 0.449 |
| hemB | actP | HMPREF0580_0362 | HMPREF0580_0367 | Porphobilinogen synthase; COG: COG0113; Pfam: PF00490; InterPro: IPR013785; Belongs to the ALAD family. | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | 0.591 |
| hemB | copA | HMPREF0580_0362 | HMPREF0580_0366 | Porphobilinogen synthase; COG: COG0113; Pfam: PF00490; InterPro: IPR013785; Belongs to the ALAD family. | Heavy metal-associated domain protein; Pfam: PF00403. | 0.415 |
| hemB | hemL | HMPREF0580_0362 | HMPREF0580_0364 | Porphobilinogen synthase; COG: COG0113; Pfam: PF00490; InterPro: IPR013785; Belongs to the ALAD family. | Glutamate-1-semialdehyde-2,1-aminomutase; COG: COG0001; Pfam: PF00202; InterPro: IPR004639. | 0.992 |