| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFM45525.1 | EFM46282.1 | HMPREF0580_1815 | HMPREF0580_1052 | AMP-binding enzyme; COG: COG0318; Pfam: PF00501; InterPro: IPR000873. | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. | 0.661 |
| EFM45525.1 | rplE | HMPREF0580_1815 | HMPREF0580_2241 | AMP-binding enzyme; COG: COG0318; Pfam: PF00501; InterPro: IPR000873. | Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.560 |
| EFM45525.1 | rplR | HMPREF0580_1815 | HMPREF0580_2237 | AMP-binding enzyme; COG: COG0318; Pfam: PF00501; InterPro: IPR000873. | Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.647 |
| EFM46282.1 | EFM45525.1 | HMPREF0580_1052 | HMPREF0580_1815 | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. | AMP-binding enzyme; COG: COG0318; Pfam: PF00501; InterPro: IPR000873. | 0.661 |
| EFM46282.1 | dpm | HMPREF0580_1052 | HMPREF0580_1503 | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. | Glycosyltransferase, group 2 family protein; COG: COG0463; Pfam: PF00535; InterPro: IPR001173. | 0.436 |
| EFM46282.1 | fadD | HMPREF0580_1052 | HMPREF0580_1299 | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. | AMP-binding enzyme; COG: COG0318; Pfam: PF00501; InterPro: IPR000873. | 0.836 |
| EFM46282.1 | gmk | HMPREF0580_1052 | HMPREF0580_1518 | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.715 |
| EFM46282.1 | menE | HMPREF0580_1052 | HMPREF0580_0665 | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. | O-succinylbenzoate-CoA ligase family protein; COG: COG0318; Pfam: PF00501; InterPro: IPR000873. | 0.702 |
| EFM46282.1 | plsC2 | HMPREF0580_1052 | HMPREF0580_1622 | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. | Acyltransferase; COG: COG0204; Pfam: PF01553; InterPro: IPR002123. | 0.451 |
| EFM46282.1 | rplE | HMPREF0580_1052 | HMPREF0580_2241 | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. | Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.815 |
| EFM46282.1 | rplR | HMPREF0580_1052 | HMPREF0580_2237 | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. | Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.631 |
| EFM46282.1 | sucA | HMPREF0580_1052 | HMPREF0580_2310 | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. | Oxoglutarate dehydrogenase (succinyl-transferring), E1 component; COG: COG0567; Pfam: PF00198,PF00676,PF02779; InterPro: IPR011603. | 0.461 |
| EFM46282.1 | valS | HMPREF0580_1052 | HMPREF0580_1053 | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. | Anticodon-binding domain protein; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner. | 0.524 |
| dpm | EFM46282.1 | HMPREF0580_1503 | HMPREF0580_1052 | Glycosyltransferase, group 2 family protein; COG: COG0463; Pfam: PF00535; InterPro: IPR001173. | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. | 0.436 |
| fadD | EFM46282.1 | HMPREF0580_1299 | HMPREF0580_1052 | AMP-binding enzyme; COG: COG0318; Pfam: PF00501; InterPro: IPR000873. | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. | 0.836 |
| fadD | rplE | HMPREF0580_1299 | HMPREF0580_2241 | AMP-binding enzyme; COG: COG0318; Pfam: PF00501; InterPro: IPR000873. | Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.560 |
| fadD | rplR | HMPREF0580_1299 | HMPREF0580_2237 | AMP-binding enzyme; COG: COG0318; Pfam: PF00501; InterPro: IPR000873. | Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.647 |
| gmk | EFM46282.1 | HMPREF0580_1518 | HMPREF0580_1052 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. | 0.715 |
| gmk | sucA | HMPREF0580_1518 | HMPREF0580_2310 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Oxoglutarate dehydrogenase (succinyl-transferring), E1 component; COG: COG0567; Pfam: PF00198,PF00676,PF02779; InterPro: IPR011603. | 0.422 |
| menE | EFM46282.1 | HMPREF0580_0665 | HMPREF0580_1052 | O-succinylbenzoate-CoA ligase family protein; COG: COG0318; Pfam: PF00501; InterPro: IPR000873. | AMP-binding enzyme; COG: COG1022; Pfam: PF00501; InterPro: IPR000873. | 0.702 |