| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFM45653.1 | EFM45856.1 | HMPREF0580_1460 | HMPREF0580_1663 | ABC transporter, ATP-binding protein; COG: COG3842; Pfam: PF00005; InterPro: IPR003593. | ABC transporter, ATP-binding protein; COG: COG1119; Pfam: PF00005; InterPro: IPR003593. | 0.425 |
| EFM45853.1 | EFM45856.1 | HMPREF0580_1660 | HMPREF0580_1663 | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078; Belongs to the phosphoglycerate mutase family. | ABC transporter, ATP-binding protein; COG: COG1119; Pfam: PF00005; InterPro: IPR003593. | 0.456 |
| EFM45853.1 | glgA | HMPREF0580_1660 | HMPREF0580_1664 | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078; Belongs to the phosphoglycerate mutase family. | Glycogen synthase, Corynebacterium family; COG: COG0438; Pfam: PF00534; InterPro: IPR011875. | 0.409 |
| EFM45853.1 | glnA2 | HMPREF0580_1660 | HMPREF0580_1662 | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078; Belongs to the phosphoglycerate mutase family. | Glutamine synthetase, beta-grasp domain protein; COG: COG0174; Pfam: PF03951,PF00120; InterPro: IPR014746. | 0.707 |
| EFM45853.1 | glnE | HMPREF0580_1660 | HMPREF0580_1661 | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078; Belongs to the phosphoglycerate mutase family. | [glutamate--ammonia-ligase] adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...] | 0.714 |
| EFM45853.1 | serB-2 | HMPREF0580_1660 | HMPREF0580_1666 | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078; Belongs to the phosphoglycerate mutase family. | Phosphoserine phosphatase SerB; COG: COG0560; Pfam: PF00702; InterPro: IPR004469. | 0.443 |
| EFM45856.1 | EFM45653.1 | HMPREF0580_1663 | HMPREF0580_1460 | ABC transporter, ATP-binding protein; COG: COG1119; Pfam: PF00005; InterPro: IPR003593. | ABC transporter, ATP-binding protein; COG: COG3842; Pfam: PF00005; InterPro: IPR003593. | 0.425 |
| EFM45856.1 | EFM45853.1 | HMPREF0580_1663 | HMPREF0580_1660 | ABC transporter, ATP-binding protein; COG: COG1119; Pfam: PF00005; InterPro: IPR003593. | Phosphoglycerate mutase family protein; Pfam: PF00300; InterPro: IPR013078; Belongs to the phosphoglycerate mutase family. | 0.456 |
| EFM45856.1 | EFM45860.1 | HMPREF0580_1663 | HMPREF0580_1667 | ABC transporter, ATP-binding protein; COG: COG1119; Pfam: PF00005; InterPro: IPR003593. | Hypothetical protein; COG: COG0028; Pfam: PF02775; InterPro: IPR011766; 1.2.3.3. | 0.461 |
| EFM45856.1 | ccmA | HMPREF0580_1663 | HMPREF0580_0986 | ABC transporter, ATP-binding protein; COG: COG1119; Pfam: PF00005; InterPro: IPR003593. | Heme ABC exporter, ATP-binding protein CcmA; COG: COG3842; Pfam: PF00005,PF08402; InterPro: IPR005895; Belongs to the ABC transporter superfamily. | 0.405 |
| EFM45856.1 | glgA | HMPREF0580_1663 | HMPREF0580_1664 | ABC transporter, ATP-binding protein; COG: COG1119; Pfam: PF00005; InterPro: IPR003593. | Glycogen synthase, Corynebacterium family; COG: COG0438; Pfam: PF00534; InterPro: IPR011875. | 0.879 |
| EFM45856.1 | glgC | HMPREF0580_1663 | HMPREF0580_1665 | ABC transporter, ATP-binding protein; COG: COG1119; Pfam: PF00005; InterPro: IPR003593. | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.697 |
| EFM45856.1 | glnA2 | HMPREF0580_1663 | HMPREF0580_1662 | ABC transporter, ATP-binding protein; COG: COG1119; Pfam: PF00005; InterPro: IPR003593. | Glutamine synthetase, beta-grasp domain protein; COG: COG0174; Pfam: PF03951,PF00120; InterPro: IPR014746. | 0.629 |
| EFM45856.1 | glnE | HMPREF0580_1663 | HMPREF0580_1661 | ABC transporter, ATP-binding protein; COG: COG1119; Pfam: PF00005; InterPro: IPR003593. | [glutamate--ammonia-ligase] adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...] | 0.622 |
| EFM45856.1 | pcm | HMPREF0580_1663 | HMPREF0580_1468 | ABC transporter, ATP-binding protein; COG: COG1119; Pfam: PF00005; InterPro: IPR003593. | Methyltransferase domain protein; COG: COG2519; Pfam: PF08241. | 0.464 |
| EFM45856.1 | serB-2 | HMPREF0580_1663 | HMPREF0580_1666 | ABC transporter, ATP-binding protein; COG: COG1119; Pfam: PF00005; InterPro: IPR003593. | Phosphoserine phosphatase SerB; COG: COG0560; Pfam: PF00702; InterPro: IPR004469. | 0.691 |
| EFM45860.1 | EFM45856.1 | HMPREF0580_1667 | HMPREF0580_1663 | Hypothetical protein; COG: COG0028; Pfam: PF02775; InterPro: IPR011766; 1.2.3.3. | ABC transporter, ATP-binding protein; COG: COG1119; Pfam: PF00005; InterPro: IPR003593. | 0.461 |
| EFM45860.1 | glgC | HMPREF0580_1667 | HMPREF0580_1665 | Hypothetical protein; COG: COG0028; Pfam: PF02775; InterPro: IPR011766; 1.2.3.3. | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.500 |
| EFM45860.1 | serB-2 | HMPREF0580_1667 | HMPREF0580_1666 | Hypothetical protein; COG: COG0028; Pfam: PF02775; InterPro: IPR011766; 1.2.3.3. | Phosphoserine phosphatase SerB; COG: COG0560; Pfam: PF00702; InterPro: IPR004469. | 0.533 |
| ccmA | EFM45856.1 | HMPREF0580_0986 | HMPREF0580_1663 | Heme ABC exporter, ATP-binding protein CcmA; COG: COG3842; Pfam: PF00005,PF08402; InterPro: IPR005895; Belongs to the ABC transporter superfamily. | ABC transporter, ATP-binding protein; COG: COG1119; Pfam: PF00005; InterPro: IPR003593. | 0.405 |