| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFM45383.1 | truB | HMPREF0580_1884 | HMPREF0580_1908 | Hypothetical protein; COG: COG0507. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.884 |
| guaA | infB | HMPREF0580_2098 | HMPREF0580_1910 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.972 |
| guaA | nusA | HMPREF0580_2098 | HMPREF0580_1911 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | 0.412 |
| guaA | rimP | HMPREF0580_2098 | HMPREF0580_1912 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.443 |
| guaA | rpsO | HMPREF0580_2098 | HMPREF0580_1904 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.752 |
| guaA | rsmB | HMPREF0580_2098 | HMPREF0580_1511 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Putative ribosomal RNA small subunit methyltransferase B; COG: COG0144; Pfam: PF01029,PF01189; InterPro: IPR001678; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.539 |
| guaA | truA | HMPREF0580_2098 | HMPREF0580_2221 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Putative tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.425 |
| guaA | truB | HMPREF0580_2098 | HMPREF0580_1908 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.976 |
| infB | guaA | HMPREF0580_1910 | HMPREF0580_2098 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.972 |
| infB | nusA | HMPREF0580_1910 | HMPREF0580_1911 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | 0.983 |
| infB | rbfA | HMPREF0580_1910 | HMPREF0580_1909 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.955 |
| infB | rimP | HMPREF0580_1910 | HMPREF0580_1912 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.835 |
| infB | rpsO | HMPREF0580_1910 | HMPREF0580_1904 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.927 |
| infB | rsmB | HMPREF0580_1910 | HMPREF0580_1511 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Putative ribosomal RNA small subunit methyltransferase B; COG: COG0144; Pfam: PF01029,PF01189; InterPro: IPR001678; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.406 |
| infB | truB | HMPREF0580_1910 | HMPREF0580_1908 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.967 |
| nusA | guaA | HMPREF0580_1911 | HMPREF0580_2098 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.412 |
| nusA | infB | HMPREF0580_1911 | HMPREF0580_1910 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.983 |
| nusA | rbfA | HMPREF0580_1911 | HMPREF0580_1909 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.778 |
| nusA | rimP | HMPREF0580_1911 | HMPREF0580_1912 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.956 |
| nusA | rpsO | HMPREF0580_1911 | HMPREF0580_1904 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.730 |