| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFM45434.1 | fmt2 | HMPREF0580_1935 | HMPREF0580_1936 | Hypothetical protein. | TIGR00730 family protein; COG: COG1611; Pfam: PF03641; InterPro: IPR005269; Belongs to the LOG family. | 0.707 |
| EFM45434.1 | manC | HMPREF0580_1935 | HMPREF0580_1937 | Hypothetical protein. | Nucleotidyl transferase; COG: COG0836; Pfam: PF00483; InterPro: IPR005835. | 0.405 |
| apt | deoD2 | HMPREF0580_1551 | HMPREF0580_1745 | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphorylases family 2; COG: COG0005; Pfam: PF00896; InterPro: IPR001369. | 0.974 |
| apt | fmt2 | HMPREF0580_1551 | HMPREF0580_1936 | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | TIGR00730 family protein; COG: COG1611; Pfam: PF03641; InterPro: IPR005269; Belongs to the LOG family. | 0.563 |
| apt | purB | HMPREF0580_1551 | HMPREF0580_0365 | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Lyase; COG: COG0015; Pfam: PF00206,PF08328; InterPro: IPR000362. | 0.973 |
| apt | tadA | HMPREF0580_1551 | HMPREF0580_0216 | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.530 |
| deoD2 | apt | HMPREF0580_1745 | HMPREF0580_1551 | Phosphorylases family 2; COG: COG0005; Pfam: PF00896; InterPro: IPR001369. | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.974 |
| deoD2 | fmt2 | HMPREF0580_1745 | HMPREF0580_1936 | Phosphorylases family 2; COG: COG0005; Pfam: PF00896; InterPro: IPR001369. | TIGR00730 family protein; COG: COG1611; Pfam: PF03641; InterPro: IPR005269; Belongs to the LOG family. | 0.517 |
| deoD2 | tadA | HMPREF0580_1745 | HMPREF0580_0216 | Phosphorylases family 2; COG: COG0005; Pfam: PF00896; InterPro: IPR001369. | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.881 |
| fmt2 | EFM45434.1 | HMPREF0580_1936 | HMPREF0580_1935 | TIGR00730 family protein; COG: COG1611; Pfam: PF03641; InterPro: IPR005269; Belongs to the LOG family. | Hypothetical protein. | 0.707 |
| fmt2 | apt | HMPREF0580_1936 | HMPREF0580_1551 | TIGR00730 family protein; COG: COG1611; Pfam: PF03641; InterPro: IPR005269; Belongs to the LOG family. | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.563 |
| fmt2 | deoD2 | HMPREF0580_1936 | HMPREF0580_1745 | TIGR00730 family protein; COG: COG1611; Pfam: PF03641; InterPro: IPR005269; Belongs to the LOG family. | Phosphorylases family 2; COG: COG0005; Pfam: PF00896; InterPro: IPR001369. | 0.517 |
| fmt2 | manC | HMPREF0580_1936 | HMPREF0580_1937 | TIGR00730 family protein; COG: COG1611; Pfam: PF03641; InterPro: IPR005269; Belongs to the LOG family. | Nucleotidyl transferase; COG: COG0836; Pfam: PF00483; InterPro: IPR005835. | 0.579 |
| fmt2 | miaA | HMPREF0580_1936 | HMPREF0580_1289 | TIGR00730 family protein; COG: COG1611; Pfam: PF03641; InterPro: IPR005269; Belongs to the LOG family. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.787 |
| fmt2 | miaB | HMPREF0580_1936 | HMPREF0580_1288 | TIGR00730 family protein; COG: COG1611; Pfam: PF03641; InterPro: IPR005269; Belongs to the LOG family. | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.615 |
| fmt2 | nrdE | HMPREF0580_1936 | HMPREF0580_0221 | TIGR00730 family protein; COG: COG1611; Pfam: PF03641; InterPro: IPR005269; Belongs to the LOG family. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.512 |
| fmt2 | purB | HMPREF0580_1936 | HMPREF0580_0365 | TIGR00730 family protein; COG: COG1611; Pfam: PF03641; InterPro: IPR005269; Belongs to the LOG family. | Lyase; COG: COG0015; Pfam: PF00206,PF08328; InterPro: IPR000362. | 0.516 |
| fmt2 | tadA | HMPREF0580_1936 | HMPREF0580_0216 | TIGR00730 family protein; COG: COG1611; Pfam: PF03641; InterPro: IPR005269; Belongs to the LOG family. | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.555 |
| fmt2 | wcaA | HMPREF0580_1936 | HMPREF0580_0235 | TIGR00730 family protein; COG: COG1611; Pfam: PF03641; InterPro: IPR005269; Belongs to the LOG family. | Glycosyltransferase, group 2 family protein; COG: COG0463; Pfam: PF00535; InterPro: IPR001173. | 0.637 |
| manC | EFM45434.1 | HMPREF0580_1937 | HMPREF0580_1935 | Nucleotidyl transferase; COG: COG0836; Pfam: PF00483; InterPro: IPR005835. | Hypothetical protein. | 0.405 |