Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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xerCPhage integrase SAM-like domain protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (361 aa)    
Predicted Functional Partners:
EFM45152.1
Hypothetical protein.
   
    0.850
apt
Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.816
EFM46586.1
Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; COG: COG0674; Pfam: PF01855,PF01558,PF00037; InterPro: IPR002869.
    
  0.807
EFM46480.1
Site-specific recombinase, phage integrase family; COG: COG0582; Pfam: PF00589; InterPro: IPR013762.
 
 
 
 0.798
EFM46268.1
FtsK/SpoIIIE family protein; COG: COG1674; Pfam: PF01580; InterPro: IPR002543.
  
   
 0.778
gltA
Citrate (Si)-synthase; COG: COG0372; Pfam: PF00285; InterPro: IPR010953; Belongs to the citrate synthase family.
     
 0.747
dprA
DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488.
 
   
 0.707
sucC
succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
  0.688
tyrA
Prephenate dehydrogenase; COG: COG0287; Pfam: PF02153,PF01842; InterPro: IPR003099.
  
    0.686
sucD
succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
     
  0.681
Your Current Organism:
Mobiluncus mulieris
NCBI taxonomy Id: 871571
Other names: M. mulieris ATCC 35239, Mobiluncus mulieris ATCC 35239, Mobiluncus mulieris str. ATCC 35239, Mobiluncus mulieris strain ATCC 35239
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