Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dprADNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. (462 aa)    
Predicted Functional Partners:
comM
Mg chelatase-like protein; COG: COG0606; Pfam: PF01078; InterPro: IPR004482.
 
 
 0.971
EFM45325.1
Hypothetical protein; Pfam: PF02021; InterPro: IPR003509; 3.1.-.-; Belongs to the UPF0102 family.
 
  
 0.939
EFM46486.1
ComEC/Rec2-like protein; Pfam: PF03772; InterPro: IPR004477.
 
  
 0.774
EFM45326.1
Hypothetical protein.
       0.773
EFM45327.1
Hypothetical protein.
       0.749
EFM45152.1
Hypothetical protein.
  
 
 0.744
xerC
Phage integrase SAM-like domain protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
 
   
 0.707
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.647
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.640
lepB-2
Signal peptidase I; COG: COG0681; Pfam: PF00717; InterPro: IPR011056; Belongs to the peptidase S26 family.
 
     0.601
Your Current Organism:
Mobiluncus mulieris
NCBI taxonomy Id: 871571
Other names: M. mulieris ATCC 35239, Mobiluncus mulieris ATCC 35239, Mobiluncus mulieris str. ATCC 35239, Mobiluncus mulieris strain ATCC 35239
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.