STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemL2Aminotransferase, class III; COG: COG0001; Pfam: PF00202; InterPro: IPR005814; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (509 aa)    
Predicted Functional Partners:
hemB
Porphobilinogen synthase; COG: COG0113; Pfam: PF00490; InterPro: IPR013785; Belongs to the ALAD family.
 
 
 0.983
hemA
glutamyl-tRNAGlu reductase domain protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.977
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.917
fucA2
Putative L-ribulose-5-phosphate 4-epimerase; COG: COG0235; Pfam: PF00596; InterPro: IPR001303.
    
  0.799
EFM47260.1
Phosphoglycerate mutase family protein; COG: COG0406; Pfam: PF00300; InterPro: IPR013078.
  
    0.754
EFM45021.1
Carbohydrate kinase, FGGY family protein; COG: COG1070; Pfam: PF00370,PF02782; InterPro: IPR000577.
 
     0.734
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.648
hemE
Putative uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.637
hemG
Putative protoporphyrinogen oxidase; Pfam: PF01593.
 
  
 0.635
EFM46845.1
Cytochrome C biogenesis protein transmembrane region; Pfam: PF02683.
  
  
 0.618
Your Current Organism:
Mobiluncus mulieris
NCBI taxonomy Id: 871571
Other names: M. mulieris ATCC 35239, Mobiluncus mulieris ATCC 35239, Mobiluncus mulieris str. ATCC 35239, Mobiluncus mulieris strain ATCC 35239
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