STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
acoCacoC; dihydrolipoamide acetyltransferase. (496 aa)    
Predicted Functional Partners:
acoD
Dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenase complexes).
 0.998
acoB
Acetoin:2,6-dichlorophenolindophenol oxidoreductase beta subunit.
 
 0.995
lpdG
Dihydrolipoamide dehydrogenase.
 0.991
acoA
Acetoin:2,6-dichlorophenolindophenol oxidoreductase alpha subunit.
 
 0.990
pdhD
Putative pyridine nucleotide-disulfide oxidoreductase, class I.
 0.982
aceE
Pyruvate decarboxylase, E1 component of the pyruvate dehydrogenase complex; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.969
gltA
Citrate synthase; Belongs to the citrate synthase family.
 
 0.954
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.950
sucA
2-oxoglutarate decarboxylase, component of the 2-oxoglutarate dehydrogenase complex (E1).
 0.941
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.940
Your Current Organism:
Acinetobacter pittii
NCBI taxonomy Id: 871585
Other names: A. pittii PHEA-2, Acinetobacter calcoaceticus PHEA-2, Acinetobacter calcoaceticus str. PHEA-2, Acinetobacter calcoaceticus strain PHEA-2, Acinetobacter pittii PHEA-2
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