STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFA75841.1Methylenetetrahydrofolate reductase (NADPH). (319 aa)    
Predicted Functional Partners:
SFA75818.1
5-methyltetrahydrofolate--homocysteine methyltransferase.
 
 
 0.996
SFA74346.1
5-methyltetrahydrofolate--homocysteine methyltransferase.
 
 
 0.972
SFA75858.1
Virulence factor.
 
    0.966
SFA73057.1
Aminomethyltransferase; Belongs to the GcvT family.
 
 
 0.916
SFA85273.1
5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family.
     
 0.916
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.891
SFB04361.1
Aminomethyltransferase.
  
 
 0.874
thyX
Thymidylate synthase (FAD); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
     
 0.873
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
  
 0.852
SFA74308.1
5-methyltetrahydrofolate--homocysteine methyltransferase.
 
 
  0.839
Your Current Organism:
Poseidonocella pacifica
NCBI taxonomy Id: 871651
Other names: DSM 29316, JCM 17310, KCTC 23693, KMM 9010, NRIC 0794, P. pacifica, Poseidonocella pacifica Romanenko et al. 2012, alpha proteobacterium KMM 9010
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