STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (655 aa)    
Predicted Functional Partners:
SFA97809.1
3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.915
SFA78829.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.911
SFB18750.1
succinyl-CoA synthetase, beta subunit.
  
 
  0.879
SFA77821.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
  
 0.869
SFA79811.1
Cation/acetate symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.821
SFA69011.1
Phosphate acetyltransferase.
  
 
 0.817
glcB
Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 0.816
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
 
 
 0.798
SFA76424.1
Methylmalonate-semialdehyde dehydrogenase [acylating].
   
  0.757
SFA88814.1
Aldehyde dehydrogenase (NAD+).
   
  0.757
Your Current Organism:
Poseidonocella pacifica
NCBI taxonomy Id: 871651
Other names: DSM 29316, JCM 17310, KCTC 23693, KMM 9010, NRIC 0794, P. pacifica, Poseidonocella pacifica Romanenko et al. 2012, alpha proteobacterium KMM 9010
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