SFA96219.1 protein (Poseidonocella pacifica)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

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gene co-occurrence

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protein homology

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[Homology]

Score

SFA96219.1

Tetratricopeptide repeat-containing protein. (199 aa)

Predicted Functional Partners:

SFA98341.1

0.898

ribB

0.846

SFA96192.1

0.803

SFA96227.1

0.771

polA

0.768

SFA96200.1

0.708

SFA96240.1

0.666

SFA86306.1

0.652

SFA96179.1

0.648

SFA90408.1

0.643

Your Current Organism:

Poseidonocella pacifica

NCBI taxonomy Id: 871651
Other names: DSM 29316, JCM 17310, KCTC 23693, KMM 9010, NRIC 0794, P. pacifica, Poseidonocella pacifica Romanenko et al. 2012, alpha proteobacterium KMM 9010

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFA86306.1	SFA90408.1	SAMN05421688_1267	SAMN05421688_1624	N-terminal double-transmembrane domain-containing protein.	TIGR02302 family protein.	0.775
SFA86306.1	SFA96219.1	SAMN05421688_1267	SAMN05421688_1899	N-terminal double-transmembrane domain-containing protein.	Tetratricopeptide repeat-containing protein.	0.652
SFA90408.1	SFA86306.1	SAMN05421688_1624	SAMN05421688_1267	TIGR02302 family protein.	N-terminal double-transmembrane domain-containing protein.	0.775
SFA90408.1	SFA96219.1	SAMN05421688_1624	SAMN05421688_1899	TIGR02302 family protein.	Tetratricopeptide repeat-containing protein.	0.643
SFA90408.1	polA	SAMN05421688_1624	SAMN05421688_1274	TIGR02302 family protein.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.522
SFA96179.1	SFA96192.1	SAMN05421688_1896	SAMN05421688_1897	Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	Heat shock protein Hsp15.	0.769
SFA96179.1	SFA96200.1	SAMN05421688_1896	SAMN05421688_1898	Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	ATP-dependent RNA helicase SUPV3L1/SUV3.	0.699
SFA96179.1	SFA96219.1	SAMN05421688_1896	SAMN05421688_1899	Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	Tetratricopeptide repeat-containing protein.	0.648
SFA96179.1	SFA96227.1	SAMN05421688_1896	SAMN05421688_1900	Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	SCP-2 sterol transfer family protein.	0.578
SFA96179.1	SFA96240.1	SAMN05421688_1896	SAMN05421688_1901	Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	Lysophospholipase.	0.576
SFA96192.1	SFA96179.1	SAMN05421688_1897	SAMN05421688_1896	Heat shock protein Hsp15.	Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	0.769
SFA96192.1	SFA96200.1	SAMN05421688_1897	SAMN05421688_1898	Heat shock protein Hsp15.	ATP-dependent RNA helicase SUPV3L1/SUV3.	0.867
SFA96192.1	SFA96219.1	SAMN05421688_1897	SAMN05421688_1899	Heat shock protein Hsp15.	Tetratricopeptide repeat-containing protein.	0.803
SFA96192.1	SFA96227.1	SAMN05421688_1897	SAMN05421688_1900	Heat shock protein Hsp15.	SCP-2 sterol transfer family protein.	0.696
SFA96192.1	SFA96240.1	SAMN05421688_1897	SAMN05421688_1901	Heat shock protein Hsp15.	Lysophospholipase.	0.696
SFA96200.1	SFA96179.1	SAMN05421688_1898	SAMN05421688_1896	ATP-dependent RNA helicase SUPV3L1/SUV3.	Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	0.699
SFA96200.1	SFA96192.1	SAMN05421688_1898	SAMN05421688_1897	ATP-dependent RNA helicase SUPV3L1/SUV3.	Heat shock protein Hsp15.	0.867
SFA96200.1	SFA96219.1	SAMN05421688_1898	SAMN05421688_1899	ATP-dependent RNA helicase SUPV3L1/SUV3.	Tetratricopeptide repeat-containing protein.	0.708
SFA96200.1	SFA96227.1	SAMN05421688_1898	SAMN05421688_1900	ATP-dependent RNA helicase SUPV3L1/SUV3.	SCP-2 sterol transfer family protein.	0.585
SFA96200.1	SFA96240.1	SAMN05421688_1898	SAMN05421688_1901	ATP-dependent RNA helicase SUPV3L1/SUV3.	Lysophospholipase.	0.585

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Network Stats

number of nodes:

11

number of edges:

23

average node degree:

4.18

avg. local clustering coefficient:

0.875

expected number of edges:

11

PPI enrichment p-value:

0.000953

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000226

Microtubule cytoskeleton organization

9 of 481

1.57

2.85

5.54e-10

GO:0007051

Spindle organization

5 of 119

1.92

2.55

2.78e-06

GO:0022402

Cell cycle process

9 of 629

1.45

2.4

3.00e-09

GO:0021987

Cerebral cortex development

4 of 57

2.15

2.38

1.79e-05

GO:0007098

Centrosome cycle

4 of 60

2.12

2.36

1.93e-05

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005815

Microtubule organizing center

8 of 610

1.42

2.1

7.36e-08

GO:0000922

Spindle pole

4 of 126

1.8

1.86

9.51e-05

GO:0005813

Centrosome

6 of 409

1.47

1.82

7.21e-06

GO:0005856

Cytoskeleton

9 of 1957

0.96

1.01

7.21e-06

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:12250

Mixed, incl. Alpha-N-methyltransferase NTM1, and Short myomegalin-like EB1 binding protein, N-terminal

3 of 7

2.93

2.51

2.61e-05

CL:12022

Mixed, incl. Anchoring of the basal body to the plasma membrane, and Gamma-tubulin complex

5 of 121

1.92

2.29

1.26e-05

CL:17111

Microtubule plus-end binding, and Mitotic cell cycle, embryonic

2 of 18

2.35

0.75

0.0420

CL:12029

Procentriole replication complex, and Loss of Nlp from mitotic centrosomes

2 of 18

2.35

0.75

0.0420

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

kmr04068

FoxO signaling pathway

3 of 156

1.58

0.96

0.0098

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00659

POLO box duplicated region

3 of 4

3.17

2.83

7.46e-06

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR039915

TACC family

3 of 4

3.17

2.56

2.34e-05

IPR007707

Transforming acidic coiled-coil-containing protein, C-terminal

3 of 4

3.17

2.56

2.34e-05

IPR000959

POLO box domain

3 of 4

3.17

2.56

2.34e-05

IPR036947

POLO box domain superfamily

2 of 3

3.12

1.32

0.0041

IPR033701

First polo-box domain

2 of 3

3.12

1.32

0.0041

(more ...)

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