SFB10499.1 protein (Poseidonocella pacifica)

Nodes:

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query proteins and first shell of interactors

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second shell of interactors

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filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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[Homology]

Score

SFB10499.1

Spermidine/putrescine transport system substrate-binding protein. (353 aa)

Predicted Functional Partners:

SFB10479.1

0.994

SFB10488.1

0.994

SFB10463.1

0.951

SFA75658.1

0.770

SFB06475.1

0.765

SFB06306.1

0.755

SFA96152.1

0.748

SFA75671.1

0.728

SFA73993.1

0.694

SFB17142.1

0.694

Your Current Organism:

Poseidonocella pacifica

NCBI taxonomy Id: 871651
Other names: DSM 29316, JCM 17310, KCTC 23693, KMM 9010, NRIC 0794, P. pacifica, Poseidonocella pacifica Romanenko et al. 2012, alpha proteobacterium KMM 9010

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFA73993.1	SFA75658.1	SAMN05421688_0510	SAMN05421688_0632	Putative spermidine/putrescine transport system permease protein.	Spermidine/putrescine transport system permease protein.	0.923
SFA73993.1	SFB06306.1	SAMN05421688_0510	SAMN05421688_2671	Putative spermidine/putrescine transport system permease protein.	Putative spermidine/putrescine transport system permease protein.	0.972
SFA73993.1	SFB06475.1	SAMN05421688_0510	SAMN05421688_2683	Putative spermidine/putrescine transport system permease protein.	Putrescine transport system permease protein.	0.983
SFA73993.1	SFB10463.1	SAMN05421688_0510	SAMN05421688_2877	Putative spermidine/putrescine transport system permease protein.	Spermidine/putrescine transport system permease protein.	0.837
SFA73993.1	SFB10488.1	SAMN05421688_0510	SAMN05421688_2879	Putative spermidine/putrescine transport system permease protein.	Spermidine/putrescine transport system ATP-binding protein; Belongs to the ABC transporter superfamily.	0.807
SFA73993.1	SFB10499.1	SAMN05421688_0510	SAMN05421688_2880	Putative spermidine/putrescine transport system permease protein.	Spermidine/putrescine transport system substrate-binding protein.	0.694
SFA75658.1	SFA73993.1	SAMN05421688_0632	SAMN05421688_0510	Spermidine/putrescine transport system permease protein.	Putative spermidine/putrescine transport system permease protein.	0.923
SFA75658.1	SFA75671.1	SAMN05421688_0632	SAMN05421688_0633	Spermidine/putrescine transport system permease protein.	Spermidine/putrescine transport system permease protein.	0.986
SFA75658.1	SFA96152.1	SAMN05421688_0632	SAMN05421688_1892	Spermidine/putrescine transport system permease protein.	Putative spermidine/putrescine transport system permease protein.	0.886
SFA75658.1	SFB06306.1	SAMN05421688_0632	SAMN05421688_2671	Spermidine/putrescine transport system permease protein.	Putative spermidine/putrescine transport system permease protein.	0.617
SFA75658.1	SFB10479.1	SAMN05421688_0632	SAMN05421688_2878	Spermidine/putrescine transport system permease protein.	Spermidine/putrescine transport system permease protein.	0.912
SFA75658.1	SFB10488.1	SAMN05421688_0632	SAMN05421688_2879	Spermidine/putrescine transport system permease protein.	Spermidine/putrescine transport system ATP-binding protein; Belongs to the ABC transporter superfamily.	0.760
SFA75658.1	SFB10499.1	SAMN05421688_0632	SAMN05421688_2880	Spermidine/putrescine transport system permease protein.	Spermidine/putrescine transport system substrate-binding protein.	0.770
SFA75658.1	SFB17142.1	SAMN05421688_0632	SAMN05421688_3386	Spermidine/putrescine transport system permease protein.	Putative spermidine/putrescine transport system permease protein.	0.908
SFA75671.1	SFA75658.1	SAMN05421688_0633	SAMN05421688_0632	Spermidine/putrescine transport system permease protein.	Spermidine/putrescine transport system permease protein.	0.986
SFA75671.1	SFB06306.1	SAMN05421688_0633	SAMN05421688_2671	Spermidine/putrescine transport system permease protein.	Putative spermidine/putrescine transport system permease protein.	0.981
SFA75671.1	SFB06475.1	SAMN05421688_0633	SAMN05421688_2683	Spermidine/putrescine transport system permease protein.	Putrescine transport system permease protein.	0.957
SFA75671.1	SFB10463.1	SAMN05421688_0633	SAMN05421688_2877	Spermidine/putrescine transport system permease protein.	Spermidine/putrescine transport system permease protein.	0.854
SFA75671.1	SFB10488.1	SAMN05421688_0633	SAMN05421688_2879	Spermidine/putrescine transport system permease protein.	Spermidine/putrescine transport system ATP-binding protein; Belongs to the ABC transporter superfamily.	0.754
SFA75671.1	SFB10499.1	SAMN05421688_0633	SAMN05421688_2880	Spermidine/putrescine transport system permease protein.	Spermidine/putrescine transport system substrate-binding protein.	0.728

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

37

average node degree:

6.73

avg. local clustering coefficient:

0.821

expected number of edges:

10

PPI enrichment p-value:

1.36e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051301

Cell division

9 of 37

1.87

4.47

4.67e-13

GO:0009252

Peptidoglycan biosynthetic process

8 of 29

1.93

4.32

9.21e-12

GO:0008360

Regulation of cell shape

7 of 25

1.94

4.05

9.69e-11

GO:0007049

Cell cycle

7 of 31

1.84

3.67

2.81e-10

GO:0071555

Cell wall organization

6 of 24

1.89

3.37

7.69e-09

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016881

Acid-amino acid ligase activity

4 of 13

1.98

1.96

0.00010

GO:0008658

Penicillin binding

2 of 4

2.19

0.79

0.0342

GO:0043168

Anion binding

7 of 518

0.62

0.36

0.0456

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0032153

Cell division site

2 of 3

2.31

1.02

0.0132

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:929

Cell shape, and Cell division site

10 of 16

2.28

7.91

2.06e-19

CL:931

Cell shape

9 of 11

2.4

7.85

5.88e-18

CL:928

Mixed, incl. Cell shape, and Cell division site

11 of 22

2.19

7.84

8.90e-21

CL:933

Mur ligase, C-terminal, and Vancomycin resistance

5 of 6

2.41

4.19

4.92e-09

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00550

Peptidoglycan biosynthesis

8 of 27

1.96

4.67

1.09e-12

map01502

Vancomycin resistance

4 of 6

2.31

3.11

7.75e-07

map00471

D-Glutamine and D-glutamate metabolism

2 of 4

2.19

1.19

0.0059

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0032153

Cell division site

3 of 9

2.01

1.43

0.0016

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0132

Cell division

9 of 33

1.92

4.93

3.12e-14

KW-0131

Cell cycle

9 of 33

1.92

4.93

3.12e-14

KW-0133

Cell shape

7 of 16

2.13

4.93

5.47e-12

KW-0573

Peptidoglycan synthesis

6 of 15

2.09

4.13

6.15e-10

KW-0961

Cell wall biogenesis/degradation

6 of 16

2.06

4.06

6.75e-10

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02875

Mur ligase family, glutamate ligase domain

3 of 4

2.36

1.77

0.00047

PF08245

Mur ligase middle domain

3 of 5

2.27

1.75

0.00047

PF03717

Penicillin-binding Protein dimerisation domain

2 of 2

2.49

1.09

0.0101

PF01225

Mur ligase family, catalytic domain

2 of 3

2.31

1.03

0.0126

PF00905

Penicillin binding protein transpeptidase domain

2 of 4

2.19

0.98

0.0151

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR004101

Mur ligase, C-terminal

3 of 4

2.36

1.57

0.0012

IPR036615

Mur ligase, C-terminal domain superfamily

3 of 5

2.27

1.55

0.0012

IPR036565

Mur-like, catalytic domain superfamily

3 of 5

2.27

1.55

0.0012

IPR013221

Mur ligase, central

3 of 5

2.27

1.55

0.0012

IPR036138

Penicillin-binding protein, dimerisation domain superfamily

2 of 2

2.49

0.98

0.0161

(more ...)

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