Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
AGA68261.1Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain. (223 aa)    
Predicted Functional Partners:
hypA
Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.952
AGA70403.1
Ni,Fe-hydrogenase III large subunit; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Nickel-dependent hydrogenase.
   
 
 0.944
AGA69955.1
Hydrogenase expression/formation protein HypD; PFAM: Hydrogenase formation hypA family.
 
  
 0.894
hypA-2
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.891
AGA69956.1
Hydrogenase assembly chaperone HypC/HupF; PFAM: HupF/HypC family.
 
  
 0.826
AGA69954.1
Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain.
 
  
 0.801
AGA69957.1
(NiFe) hydrogenase maturation protein HypF; PFAM: HypF finger; yrdC domain; Acylphosphatase.
 
   
 0.756
AGA68259.1
4Fe-4S protein.
 
    0.727
AGA68258.1
acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; PFAM: AMP-binding enzyme.
       0.480
AGA68262.1
Arabinose efflux permease family protein; PFAM: Major Facilitator Superfamily.
     
 0.446
Your Current Organism:
Desulfitobacterium dichloroeliminans
NCBI taxonomy Id: 871963
Other names: D. dichloroeliminans LMG P-21439, Desulfitobacterium dichloroeliminans DCA1, Desulfitobacterium dichloroeliminans LMG P-21439, Desulfitobacterium dichloroeliminans LMG P21439, Desulfitobacterium dichloroeliminans str. LMG P-21439, Desulfitobacterium dichloroeliminans strain LMG P-21439
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