Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGA69596.1PFAM: HpcH/HpaI aldolase/citrate lyase family; Belongs to the HpcH/HpaI aldolase family. (295 aa)    
Predicted Functional Partners:
AGA70331.1
PFAM: Citrate lyase, alpha subunit (CitF).
 
  
 0.937
AGA70333.1
Citrate lyase acyl carrier protein; Covalent carrier of the coenzyme of citrate lyase.
 
  
 0.927
AGA70332.1
PFAM: HpcH/HpaI aldolase/citrate lyase family; Belongs to the HpcH/HpaI aldolase family.
  
  
 
0.920
AGA68194.1
PFAM: HpcH/HpaI aldolase/citrate lyase family; Belongs to the HpcH/HpaI aldolase family.
  
  
 
0.902
AGA70069.1
Ribulose-5-phosphate 4-epimerase-like epimerase or aldolase; PFAM: Class II Aldolase and Adducin N-terminal domain.
   
    0.736
AGA69595.1
PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
  
  
 0.601
AGA69599.1
PFAM: ATP-grasp domain; TIGRFAM: succinyl-CoA synthetase, beta subunit.
 
   
 0.573
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
  
 0.565
AGA69857.1
acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: HMGL-like; Biotin-requiring enzyme; Conserved carboxylase domain.
  
  
 0.559
AGA67597.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; PFAM: Domain of unknown function; domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
  
  
 0.411
Your Current Organism:
Desulfitobacterium dichloroeliminans
NCBI taxonomy Id: 871963
Other names: D. dichloroeliminans LMG P-21439, Desulfitobacterium dichloroeliminans DCA1, Desulfitobacterium dichloroeliminans LMG P-21439, Desulfitobacterium dichloroeliminans LMG P21439, Desulfitobacterium dichloroeliminans str. LMG P-21439, Desulfitobacterium dichloroeliminans strain LMG P-21439
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