| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGA69486.1 | recR | Desdi_2041 | Desdi_0022 | DNA segregation ATPase, FtsK/SpoIIIE family; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family; Belongs to the FtsK/SpoIIIE/SftA family. | DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.539 |
| AGA69486.1 | topA | Desdi_2041 | Desdi_2604 | DNA segregation ATPase, FtsK/SpoIIIE family; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family; Belongs to the FtsK/SpoIIIE/SftA family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.474 |
| AGA69486.1 | xerC-2 | Desdi_2041 | Desdi_2602 | DNA segregation ATPase, FtsK/SpoIIIE family; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family; Belongs to the FtsK/SpoIIIE/SftA family. | Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.660 |
| AGA69631.1 | recR | Desdi_2190 | Desdi_0022 | DNA segregation ATPase, FtsK/SpoIIIE family; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family. | DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.537 |
| AGA69631.1 | topA | Desdi_2190 | Desdi_2604 | DNA segregation ATPase, FtsK/SpoIIIE family; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.474 |
| AGA69631.1 | xerC-2 | Desdi_2190 | Desdi_2602 | DNA segregation ATPase, FtsK/SpoIIIE family; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family. | Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.658 |
| AGA70021.1 | AGA70798.1 | Desdi_2605 | Desdi_3412 | PFAM: DNA recombination-mediator protein A. | Putative amidophosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain. | 0.915 |
| AGA70021.1 | codY | Desdi_2605 | Desdi_2599 | PFAM: DNA recombination-mediator protein A. | GTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | 0.472 |
| AGA70021.1 | hslU | Desdi_2605 | Desdi_2600 | PFAM: DNA recombination-mediator protein A. | ATP-dependent protease HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.509 |
| AGA70021.1 | hslV | Desdi_2605 | Desdi_2601 | PFAM: DNA recombination-mediator protein A. | ATP dependent peptidase CodWX, CodW component; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.549 |
| AGA70021.1 | recR | Desdi_2605 | Desdi_0022 | PFAM: DNA recombination-mediator protein A. | DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.621 |
| AGA70021.1 | topA | Desdi_2605 | Desdi_2604 | PFAM: DNA recombination-mediator protein A. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.853 |
| AGA70021.1 | trmFO | Desdi_2605 | Desdi_2603 | PFAM: DNA recombination-mediator protein A. | tRNA:m(5)U-54 methyltransferase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.643 |
| AGA70021.1 | xerC-2 | Desdi_2605 | Desdi_2602 | PFAM: DNA recombination-mediator protein A. | Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.584 |
| AGA70798.1 | AGA70021.1 | Desdi_3412 | Desdi_2605 | Putative amidophosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain. | PFAM: DNA recombination-mediator protein A. | 0.915 |
| AGA70798.1 | xerC-2 | Desdi_3412 | Desdi_2602 | Putative amidophosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain. | Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.504 |
| codY | AGA70021.1 | Desdi_2599 | Desdi_2605 | GTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | PFAM: DNA recombination-mediator protein A. | 0.472 |
| codY | hslU | Desdi_2599 | Desdi_2600 | GTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | ATP-dependent protease HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.787 |
| codY | hslV | Desdi_2599 | Desdi_2601 | GTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | ATP dependent peptidase CodWX, CodW component; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.758 |
| codY | topA | Desdi_2599 | Desdi_2604 | GTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.697 |
