STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iolSOxidoreductase, aldo/keto reductase family protein; Identified by match to protein family HMM PF00248. (328 aa)    
Predicted Functional Partners:
cypB
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
   0.813
glpF2
Identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.791
glpF1
Putative glycerol facilitator-aquaporin; Identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.791
gla
Glycerol facilitator-aquaporin; Identified by match to protein family HMM PF00230; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.791
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 
 0.789
lip2
Hypothetical protein.
  
 
 0.778
EGJ27026.1
Putative serine/threonine phosphatase stp; Identified by match to protein family HMM PF00481.
    
   0.770
EGJ26594.1
Putative glyoxal reductase; Identified by match to protein family HMM PF00248.
 
0.763
EGJ26890.1
Identified by match to protein family HMM PF04909.
  
 
 0.747
suhB
Identified by match to protein family HMM PF00459.
   
 
 0.739
Your Current Organism:
Streptococcus porcinus
NCBI taxonomy Id: 873448
Other names: S. porcinus str. Jelinkova 176, Streptococcus porcinus str. Jelinkova 176, Streptococcus porcinus strain Jelinkova 176
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