STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGJ27921.1Sugar-specific transcriptional regulator, TrmB family; Identified by match to protein family HMM PF01978. (261 aa)    
Predicted Functional Partners:
EGJ27318.1
Putative membrane protein.
 
     0.935
EGJ27325.1
Identified by match to protein family HMM PF02423.
 
     0.921
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
    0.707
EGJ27301.1
Putative membrane protein.
 
     0.535
graR
Putative response regulator protein GraR; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
       0.448
EGJ27079.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF02518.
       0.448
Your Current Organism:
Streptococcus porcinus
NCBI taxonomy Id: 873448
Other names: S. porcinus str. Jelinkova 176, Streptococcus porcinus str. Jelinkova 176, Streptococcus porcinus strain Jelinkova 176
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.