STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
srtAIdentified by match to protein family HMM PF04203; match to protein family HMM TIGR01076. (252 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.860
EGJ26957.1
Identified by match to protein family HMM PF00903.
       0.641
EGJ28229.1
LPXTG-motif cell wall anchor domain protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF05738; match to protein family HMM TIGR01167.
 
  
 0.632
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
    0.559
mur1.1
Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Identified by match to protein family HMM PF01832.
  
     0.503
EGJ27224.1
Muramidase-2; Identified by match to protein family HMM PF01832.
  
     0.449
recJ
single-stranded-DNA-specific exonuclease RecJ; Identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644.
     
 0.436
metG_1
Hypothetical protein.
  
     0.430
EGJ27623.1
Identified by match to protein family HMM PF06207.
       0.422
EGJ26424.1
Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Identified by match to protein family HMM PF01832.
  
     0.417
Your Current Organism:
Streptococcus porcinus
NCBI taxonomy Id: 873448
Other names: S. porcinus str. Jelinkova 176, Streptococcus porcinus str. Jelinkova 176, Streptococcus porcinus strain Jelinkova 176
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.