| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| folB | folE | STRPO_0475 | STRPO_0477 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | 0.996 |
| folB | folK | STRPO_0475 | STRPO_0474 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498. | 0.999 |
| folB | folP | STRPO_0475 | STRPO_0476 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.998 |
| folB | murB | STRPO_0475 | STRPO_0473 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.569 |
| folB | potA_1 | STRPO_0475 | STRPO_0472 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | ABC transporter, ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. | 0.507 |
| folB | potB | STRPO_0475 | STRPO_0471 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Putative spermidine/putrescine ABC transporter, permease protein PotB. | 0.507 |
| folB | potC | STRPO_0475 | STRPO_0470 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Putative spermidine/putrescine ABC transporter, permease protein PotC; Identified by match to protein family HMM PF00528. | 0.507 |
| folB | potD | STRPO_0475 | STRPO_0469 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Putative spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein PotD; identified by match to protein family HMM PF01547. | 0.507 |
| folE | folB | STRPO_0477 | STRPO_0475 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.996 |
| folE | folK | STRPO_0477 | STRPO_0474 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498. | 0.999 |
| folE | folP | STRPO_0477 | STRPO_0476 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.998 |
| folE | murB | STRPO_0477 | STRPO_0473 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.558 |
| folE | potA_1 | STRPO_0477 | STRPO_0472 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | ABC transporter, ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. | 0.497 |
| folE | potB | STRPO_0477 | STRPO_0471 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Putative spermidine/putrescine ABC transporter, permease protein PotB. | 0.515 |
| folE | potC | STRPO_0477 | STRPO_0470 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Putative spermidine/putrescine ABC transporter, permease protein PotC; Identified by match to protein family HMM PF00528. | 0.510 |
| folE | potD | STRPO_0477 | STRPO_0469 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Putative spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein PotD; identified by match to protein family HMM PF01547. | 0.510 |
| folK | folB | STRPO_0474 | STRPO_0475 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| folK | folE | STRPO_0474 | STRPO_0477 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498. | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | 0.999 |
| folK | folP | STRPO_0474 | STRPO_0476 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
| folK | murB | STRPO_0474 | STRPO_0473 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.680 |