STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498. (163 aa)    
Predicted Functional Partners:
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 0.999
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 0.999
folE
GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.
  
 0.999
folC
Bifunctional protein FolC; Identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family.
 
 
 0.968
pabB
Aminodeoxychorismate synthase, component I; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553.
 
 
 0.965
apbA
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.747
pyk
Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM PF03328; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
    
  0.725
relA
GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
  0.724
EGJ26831.1
Putative F420-0:gamma-glutamyl ligase.
    
  0.708
EGJ27877.1
Dinuclear metal center protein, YbgI family; Identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486.
    
  0.707
Your Current Organism:
Streptococcus porcinus
NCBI taxonomy Id: 873448
Other names: S. porcinus str. Jelinkova 176, Streptococcus porcinus str. Jelinkova 176, Streptococcus porcinus strain Jelinkova 176
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.