STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvaShydroxymethylglutaryl-CoA synthase; Identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835. (390 aa)    
Predicted Functional Partners:
mvaA
hydroxymethylglutaryl-CoA reductase, degradative; Identified by match to protein family HMM TIGR00532; Belongs to the HMG-CoA reductase family.
 
 0.999
mvaD
Diphosphomevalonate decarboxylase; Identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01240.
 
 
 0.918
mvk
Mevalonate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR00549.
 
 
 0.917
mvaK2
Phosphomevalonate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01220.
 
 
 0.915
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
 
 0.873
dltC
D-alanine--poly(phosphoribitol) ligase, subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
  
 0.864
acpB
Putative acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 0.864
EGJ27960.1
Putative acyl carrier protein; Identified by match to protein family HMM PF00550.
  
 0.864
paaG
Identified by match to protein family HMM PF00378.
  
 
 0.813
fabF
Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
 
 0.781
Your Current Organism:
Streptococcus porcinus
NCBI taxonomy Id: 873448
Other names: S. porcinus str. Jelinkova 176, Streptococcus porcinus str. Jelinkova 176, Streptococcus porcinus strain Jelinkova 176
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