| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EGJ27028.1 | murI | STRPO_0894 | STRPO_0896 | Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.796 |
| EGJ27028.1 | rdgB | STRPO_0894 | STRPO_0895 | Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040. | Non-canonical purine NTP pyrophosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.940 |
| EGJ27028.1 | scpA_6 | STRPO_0894 | STRPO_0891 | Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040. | ScpA/B protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.796 |
| EGJ27028.1 | scpB | STRPO_0894 | STRPO_0890 | Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040. | Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.801 |
| EGJ27028.1 | xerD | STRPO_0894 | STRPO_0892 | Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040. | Site-specific tyrosine recombinase XerD-like protein; Putative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site. Belongs to the 'phage' integrase family. XerD-like subfamily. | 0.796 |
| EGJ27028.1 | ykuL | STRPO_0894 | STRPO_0893 | Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040. | CBS domain protein; Identified by match to protein family HMM PF00571. | 0.849 |
| asnB | gdhA | STRPO_1087 | STRPO_0519 | Asparaginase; Identified by match to protein family HMM PF00710. | NAD(P)-specific glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.732 |
| asnB | murI | STRPO_1087 | STRPO_0896 | Asparaginase; Identified by match to protein family HMM PF00710. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.718 |
| gdhA | asnB | STRPO_0519 | STRPO_1087 | NAD(P)-specific glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Asparaginase; Identified by match to protein family HMM PF00710. | 0.732 |
| gdhA | guaB | STRPO_0519 | STRPO_1378 | NAD(P)-specific glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.526 |
| gdhA | murI | STRPO_0519 | STRPO_0896 | NAD(P)-specific glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.757 |
| guaB | gdhA | STRPO_1378 | STRPO_0519 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | NAD(P)-specific glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.526 |
| guaB | murI | STRPO_1378 | STRPO_0896 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.817 |
| guaB | rdgB | STRPO_1378 | STRPO_0895 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Non-canonical purine NTP pyrophosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.883 |
| guaB | ykuL | STRPO_1378 | STRPO_0893 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | CBS domain protein; Identified by match to protein family HMM PF00571. | 0.817 |
| murD | murI | STRPO_1919 | STRPO_0896 | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.966 |
| murD | rdgB | STRPO_1919 | STRPO_0895 | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Non-canonical purine NTP pyrophosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.712 |
| murI | EGJ27028.1 | STRPO_0896 | STRPO_0894 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040. | 0.796 |
| murI | asnB | STRPO_0896 | STRPO_1087 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Asparaginase; Identified by match to protein family HMM PF00710. | 0.718 |
| murI | gdhA | STRPO_0896 | STRPO_0519 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | NAD(P)-specific glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.757 |