STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dapE_2Peptidase dimerization domain protein; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687. (457 aa)    
Predicted Functional Partners:
atmD
ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
     
 0.818
metI
D-methionine transport system permease protein MetI; Identified by match to protein family HMM PF00528.
       0.796
gshAB
Glutamate--cysteine ligase/gamma-glutamylcysteine synthetase; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
     
 0.783
metQ
Putative D-methionine-binding lipoprotein MetQ; Identified by match to protein family HMM PF03180; Belongs to the nlpA lipoprotein family.
       0.567
glmS
Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 
 0.542
pepN
Membrane alanyl aminopeptidase; Identified by match to protein family HMM PF01433.
   
 0.450
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.449
pabB
Aminodeoxychorismate synthase, component I; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553.
  
 0.433
EGJ26759.1
Plasmid replication protein; Identified by match to protein family HMM PF01719.
  
 0.430
yqeH
Ribosome biogenesis GTPase YqeH; Identified by match to protein family HMM PF01926; match to protein family HMM TIGR03597.
   
  0.424
Your Current Organism:
Streptococcus porcinus
NCBI taxonomy Id: 873448
Other names: S. porcinus str. Jelinkova 176, Streptococcus porcinus str. Jelinkova 176, Streptococcus porcinus strain Jelinkova 176
Server load: low (14%) [HD]