STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysKCysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family. (308 aa)    
Predicted Functional Partners:
cysE
Serine O-acetyltransferase; Identified by match to protein family HMM TIGR01172.
 
 0.992
cysS
cysteine--tRNA ligase; Identified by match to protein family HMM PF01406; match to protein family HMM PF09190; match to protein family HMM PF09334; match to protein family HMM TIGR00435; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.956
gshAB
Glutamate--cysteine ligase/gamma-glutamylcysteine synthetase; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
     
 0.861
luxS
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
 
 0.806
EGJ27325.1
Identified by match to protein family HMM PF02423.
  
 
 0.790
serC
Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
  
 
 0.761
pepN
Membrane alanyl aminopeptidase; Identified by match to protein family HMM PF01433.
     
 0.720
coaC
Phosphopantothenoylcysteine decarboxylase; Identified by match to protein family HMM PF02441; match to protein family HMM TIGR02113.
    
  0.705
coaB
Phosphopantothenate--cysteine ligase; Identified by match to protein family HMM PF04127; match to protein family HMM TIGR02114.
    
  0.705
EGJ27559.1
Pyridine nucleotide-disulfide oxidoreductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992.
     
 0.700
Your Current Organism:
Streptococcus porcinus
NCBI taxonomy Id: 873448
Other names: S. porcinus str. Jelinkova 176, Streptococcus porcinus str. Jelinkova 176, Streptococcus porcinus strain Jelinkova 176
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