STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
codYGTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. (260 aa)    
Predicted Functional Partners:
yecD
Identified by match to protein family HMM PF00857.
       0.796
msrR
Cell envelope-like function transcriptional attenuator common domain protein; Identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350.
  
   
 0.636
ccpA
Identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481.
    
 
 0.603
EGJ27282.1
Identified by match to protein family HMM PF03780.
  
     0.574
purR
Pur operon repressor PurR; Identified by match to protein family HMM PF00156; match to protein family HMM PF09182; match to protein family HMM TIGR01743.
  
  
 0.542
sepF
Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
    0.526
EGJ27812.1
Putative aminotransferase AlaT; Identified by match to protein family HMM PF00155; match to protein family HMM PF01212.
     
 0.521
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.519
EGJ27189.1
CHAP domain protein; Identified by match to protein family HMM PF05257.
  
   
 0.473
EGJ26905.1
Helix-turn-helix protein, YlxM/p13 family; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
     0.471
Your Current Organism:
Streptococcus porcinus
NCBI taxonomy Id: 873448
Other names: S. porcinus str. Jelinkova 176, Streptococcus porcinus str. Jelinkova 176, Streptococcus porcinus strain Jelinkova 176
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.