STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGJ26635.1Transporter, major facilitator family protein; Identified by match to protein family HMM PF07690. (429 aa)    
Predicted Functional Partners:
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
    0.903
aroD_2
3-dehydroquinate dehydratase, type I; Identified by match to protein family HMM PF01487; match to protein family HMM TIGR01093.
 
     0.829
EGJ28320.1
Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466.
 
    0.808
pabB
Aminodeoxychorismate synthase, component I; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553.
   
 
 0.773
ydiM
Transporter, major facilitator family protein; Identified by match to protein family HMM PF07690.
 
    
0.721
EGJ27239.1
Identified by match to protein family HMM PF01261.
 
    0.697
EGJ27394.1
Oxidoreductase, short chain dehydrogenase/reductase family protein; Identified by match to protein family HMM PF00106.
 
     0.689
aroD_1
3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
 
     0.656
EGJ27907.1
Identified by match to protein family HMM PF00724; match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF04205; match to protein family HMM PF07992.
 
 
 0.610
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
  0.436
Your Current Organism:
Streptococcus porcinus
NCBI taxonomy Id: 873448
Other names: S. porcinus str. Jelinkova 176, Streptococcus porcinus str. Jelinkova 176, Streptococcus porcinus strain Jelinkova 176
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