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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iolCCarbohydrate kinase, PfkB family; Identified by match to protein family HMM PF00294. (341 aa)    
Predicted Functional Partners:
eda
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to protein family HMM PF01081; match to protein family HMM TIGR01182.
 
 
 0.987
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.975
fruA
PTS system protein fructose-specific EIIABC component; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427.
  
 
 0.910
guaA
GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.890
uxaC
Glucuronate isomerase; Identified by match to protein family HMM PF02614.
 
   
 0.865
uidA_2
Glycosyl hydrolase family 2, TIM barrel domain protein; Identified by match to protein family HMM PF00703; match to protein family HMM PF02836; match to protein family HMM PF02837; Belongs to the glycosyl hydrolase 2 family.
 
  
 0.858
EGJ26423.1
Oxidoreductase, short chain dehydrogenase/reductase family protein; Identified by match to protein family HMM PF00106; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.838
manX
PTS system protein mannose-specific EIIAB component; Identified by match to protein family HMM PF03610; match to protein family HMM PF03830.
  
 
 0.831
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.831
rpe
Ribulose-phosphate 3-epimerase; Identified by match to protein family HMM PF00215; match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.824
Your Current Organism:
Streptococcus porcinus
NCBI taxonomy Id: 873448
Other names: S. porcinus str. Jelinkova 176, Streptococcus porcinus str. Jelinkova 176, Streptococcus porcinus strain Jelinkova 176
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