STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iolCCarbohydrate kinase, PfkB family; Identified by match to protein family HMM PF00294. (341 aa)    
Predicted Functional Partners:
eda
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to protein family HMM PF01081; match to protein family HMM TIGR01182.
 
 
 0.994
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.976
uidA_2
Glycosyl hydrolase family 2, TIM barrel domain protein; Identified by match to protein family HMM PF00703; match to protein family HMM PF02836; match to protein family HMM PF02837; Belongs to the glycosyl hydrolase 2 family.
 
   
 0.905
uxaC
Glucuronate isomerase; Identified by match to protein family HMM PF02614.
 
   
 0.898
rpe
Ribulose-phosphate 3-epimerase; Identified by match to protein family HMM PF00215; match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.859
EGJ28277.1
Putative ribulose-phosphate 3-epimerase; Identified by match to protein family HMM PF00834.
  
 0.859
uidB
Putative ATP synthase F0, A subunit.
 
  
 0.859
pdhR
FCD domain protein; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729.
 
     0.802
EGJ26423.1
Oxidoreductase, short chain dehydrogenase/reductase family protein; Identified by match to protein family HMM PF00106; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 
 0.797
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.666
Your Current Organism:
Streptococcus porcinus
NCBI taxonomy Id: 873448
Other names: S. porcinus str. Jelinkova 176, Streptococcus porcinus str. Jelinkova 176, Streptococcus porcinus strain Jelinkova 176
Server load: medium (46%) [HD]