Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EGJ26423.1Oxidoreductase, short chain dehydrogenase/reductase family protein; Identified by match to protein family HMM PF00106; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (279 aa)    
Predicted Functional Partners:
uxaC
Glucuronate isomerase; Identified by match to protein family HMM PF02614.
 
  
 0.940
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.913
eda
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to protein family HMM PF01081; match to protein family HMM TIGR01182.
 
  
 0.828
EGJ27747.1
Haloacid dehalogenase-like hydrolase; Identified by match to protein family HMM PF00702.
 
    0.814
iolC
Carbohydrate kinase, PfkB family; Identified by match to protein family HMM PF00294.
 
 
 
 0.797
nag3
Putative beta-N-acetylglucosaminidase/beta-glucosidase; Identified by match to protein family HMM PF00933.
 
   
 0.701
uidB
Putative ATP synthase F0, A subunit.
 
   
 0.673
pdhR
FCD domain protein; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729.
 
     0.650
uidA_2
Glycosyl hydrolase family 2, TIM barrel domain protein; Identified by match to protein family HMM PF00703; match to protein family HMM PF02836; match to protein family HMM PF02837; Belongs to the glycosyl hydrolase 2 family.
 
   
 0.590
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.546
Your Current Organism:
Streptococcus porcinus
NCBI taxonomy Id: 873448
Other names: S. porcinus str. Jelinkova 176, Streptococcus porcinus str. Jelinkova 176, Streptococcus porcinus strain Jelinkova 176
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