Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gshABGlutathione biosynthesis bifunctional protein gshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily. (751 aa)    
Predicted Functional Partners:
EHI75068.1
Putative cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.949
EHI74588.1
Putative glutamate--ammonia ligase; Belongs to the glutamine synthetase family.
    
 0.944
gdhA
NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.942
pepN
Membrane alanyl aminopeptidase.
   
 
 0.921
ilvE
Branched-chain-amino-acid transaminase.
   
 
 0.919
EHI73635.1
Hypothetical protein; Belongs to the aspartate/glutamate racemases family.
     
  0.911
EHI73315.1
Aminotransferase, class II.
     
  0.911
EHI74688.1
Alcohol dehydrogenase, iron-dependent; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
    
 0.905
EHI75029.1
Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.
  
 
 0.892
EHI73931.1
Cystathionine gamma-synthase.
    
 0.854
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
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