Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHI74492.1Thioredoxin family protein. (105 aa)    
Predicted Functional Partners:
msrA
Peptide methionine sulfoxide reductase MsrA/msrB family protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.988
EHI73312.1
Putative membrane protein.
   
 0.945
dnaJ
Putative chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]
    
 0.892
dnaK
Putative chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.869
EHI75334.1
Hypothetical protein.
       0.846
trxB
Thioredoxin-disulfide reductase.
  
 0.837
EHI73610.1
Putative ferredoxin--NADP(+) reductase.
  
 0.837
EHI74338.1
tRNA binding domain protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.820
EHI75079.1
Ribonucleotide-pyrophosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
   
 0.786
pepA
Glutamyl aminopeptidase.
       0.744
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
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