Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (256 aa)    
Predicted Functional Partners:
EHI73635.1
Hypothetical protein; Belongs to the aspartate/glutamate racemases family.
     
  0.910
proA
Putative Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.894
proB
Putative glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.872
pepA
Glutamyl aminopeptidase.
  
    0.762
EHI74067.1
Phosphoribosylformylglycinamidine synthase.
     
 0.723
EHI74492.1
Thioredoxin family protein.
     
 0.681
EHI75334.1
Hypothetical protein.
       0.677
EHI73947.1
Putative formate C-acetyltransferase.
    
 0.673
pflD
Formate C-acetyltransferase.
    
 0.673
EHI74338.1
tRNA binding domain protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.662
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
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