Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
esxAType VII secretion system protein EsxA; Belongs to the WXG100 family. (97 aa)    
Predicted Functional Partners:
essB
Type VII secretion protein EssB.
 
  
 0.948
EHI73330.1
Type VII secretion protein EsaA family protein.
 
   
 0.946
essC_1
Type VII secretion protein EssC.
 
 
 0.943
essC_2
Type VII secretion protein EssC.
 
 
 0.922
essC_3
Type VII secretion protein EssC.
 
 
 0.922
EHI74104.1
Putative DNA translocase FtsK; Belongs to the FtsK/SpoIIIE/SftA family.
  
 
 0.665
EHI75565.1
Hypothetical protein; Identified by glimmer; putative.
       0.432
EHI74602.1
Putative membrane protein.
 
   
 0.432
EHI75083.1
Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the UPF0342 family.
  
     0.420
EHI73869.1
Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.
       0.419
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
Server load: medium (52%) [HD]