Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EHI74372.1Rod shape-determining protein MreC family protein; Involved in formation and maintenance of cell shape. (276 aa)    
Predicted Functional Partners:
EHI73727.1
Rod shape-determining protein MreD family protein.
  
 
 0.997
EHI75171.1
Penicillin-binding protein 2B family protein.
 
 
 0.976
EHI73737.1
Cell division protein, FtsW/RodA/SpoVE family; Belongs to the SEDS family.
 
  
 0.932
pbpX
Penicillin-binding protein 2X.
 
 
 0.921
gpsB
Cell cycle protein GpsB family protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
  
 
 0.919
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
  
 0.871
pbp2A
Penicillin-binding protein 2A.
  
 
 0.864
pbp1A
Penicillin-binding protein 1A.
  
 
 0.858
ftsW
Cell division protein, FtsW/RodA/SpoVE family; Belongs to the SEDS family.
  
  
 0.857
EHI73783.1
Septum site-determining protein divIVA family protein.
   
 
 0.838
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
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