Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
pxpAHypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (257 aa)    
Predicted Functional Partners:
kipI
Kinase A inhibitor.
 
 0.999
EHI74773.1
Hypothetical protein.
 
 0.993
EHI74055.1
Putative membrane protein.
 
  
 0.952
accC
Biotin carboxylase 1.
  
    0.771
gshAB
Glutathione biosynthesis bifunctional protein gshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
     
  0.761
EHI74588.1
Putative glutamate--ammonia ligase; Belongs to the glutamine synthetase family.
   
 
  0.723
gdhA
NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
  0.716
EHI74067.1
Phosphoribosylformylglycinamidine synthase.
     
  0.690
EHI74689.1
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
     
  0.617
gapN
Glyceraldehyde-3-phosphate dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family.
     
  0.617
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
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