Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
pbp1BPenicillin-binding protein 1B. (803 aa)    
Predicted Functional Partners:
pbpX
Penicillin-binding protein 2X.
  
 
 0.994
EHI75171.1
Penicillin-binding protein 2B family protein.
  
 0.993
dacA
Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family.
   
 
 0.950
pbp1A
Penicillin-binding protein 1A.
  
  
0.936
pbp2A
Penicillin-binding protein 2A.
  
  
0.935
EHI74414.1
Serine-type D-Ala-D-Ala carboxypeptidase.
     
 0.911
EHI74428.1
Bsp family protein.
     
 0.911
gpsB
Cell cycle protein GpsB family protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
   
 
 0.837
EHI73737.1
Cell division protein, FtsW/RodA/SpoVE family; Belongs to the SEDS family.
  
 
 
 0.832
ftsW
Cell division protein, FtsW/RodA/SpoVE family; Belongs to the SEDS family.
  
 
 
 0.824
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
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