| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EHI73332.1 | clpP | STRCR_2190 | STRCR_2338 | ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.880 |
| EHI73332.1 | dnaJ | STRCR_2190 | STRCR_0591 | ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family. | Putative chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...] | 0.702 |
| EHI73332.1 | dnaK | STRCR_2190 | STRCR_0590 | ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family. | Putative chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.895 |
| EHI73332.1 | groES | STRCR_2190 | STRCR_0167 | ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family. | Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.497 |
| EHI73332.1 | groL | STRCR_2190 | STRCR_0166 | ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family. | Putative chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.502 |
| EHI73332.1 | grpE | STRCR_2190 | STRCR_0589 | ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family. | Putative protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-de [...] | 0.666 |
| EHI73332.1 | hrcA | STRCR_2190 | STRCR_0588 | ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family. | Putative Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.432 |
| EHI73893.1 | clpP | STRCR_0904 | STRCR_2338 | Hypothetical protein; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.876 |
| EHI73893.1 | dnaJ | STRCR_0904 | STRCR_0591 | Hypothetical protein; Belongs to the ClpA/ClpB family. | Putative chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...] | 0.705 |
| EHI73893.1 | dnaK | STRCR_0904 | STRCR_0590 | Hypothetical protein; Belongs to the ClpA/ClpB family. | Putative chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.903 |
| EHI73893.1 | groES | STRCR_0904 | STRCR_0167 | Hypothetical protein; Belongs to the ClpA/ClpB family. | Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.497 |
| EHI73893.1 | groL | STRCR_0904 | STRCR_0166 | Hypothetical protein; Belongs to the ClpA/ClpB family. | Putative chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.540 |
| EHI73893.1 | grpE | STRCR_0904 | STRCR_0589 | Hypothetical protein; Belongs to the ClpA/ClpB family. | Putative protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-de [...] | 0.666 |
| EHI73893.1 | hrcA | STRCR_0904 | STRCR_0588 | Hypothetical protein; Belongs to the ClpA/ClpB family. | Putative Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.430 |
| EHI74743.1 | clpP | STRCR_0237 | STRCR_2338 | Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.842 |
| EHI74743.1 | dnaJ | STRCR_0237 | STRCR_0591 | Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. | Putative chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...] | 0.689 |
| EHI74743.1 | dnaK | STRCR_0237 | STRCR_0590 | Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. | Putative chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.891 |
| EHI74743.1 | groES | STRCR_0237 | STRCR_0167 | Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. | Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.476 |
| EHI74743.1 | groL | STRCR_0237 | STRCR_0166 | Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. | Putative chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.477 |
| EHI74743.1 | grpE | STRCR_0237 | STRCR_0589 | Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. | Putative protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-de [...] | 0.654 |
STRING v12.5 is now available!
