| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EHI74067.1 | awd | STRCR_0450 | STRCR_1200 | Phosphoribosylformylglycinamidine synthase. | Nucleoside pyrophosphate kinase. | 0.794 |
| EHI74067.1 | fusA | STRCR_0450 | STRCR_0692 | Phosphoribosylformylglycinamidine synthase. | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | 0.441 |
| EHI74067.1 | guaA | STRCR_0450 | STRCR_1553 | Phosphoribosylformylglycinamidine synthase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.993 |
| EHI74067.1 | guaB | STRCR_0450 | STRCR_0387 | Phosphoribosylformylglycinamidine synthase. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.969 |
| EHI74067.1 | ileS | STRCR_0450 | STRCR_2198 | Phosphoribosylformylglycinamidine synthase. | Putative isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.533 |
| EHI74067.1 | pyrG | STRCR_0450 | STRCR_0599 | Phosphoribosylformylglycinamidine synthase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.849 |
| EHI74067.1 | rpoB | STRCR_0450 | STRCR_0555 | Phosphoribosylformylglycinamidine synthase. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.814 |
| awd | EHI74067.1 | STRCR_1200 | STRCR_0450 | Nucleoside pyrophosphate kinase. | Phosphoribosylformylglycinamidine synthase. | 0.794 |
| awd | fusA | STRCR_1200 | STRCR_0692 | Nucleoside pyrophosphate kinase. | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | 0.514 |
| awd | guaA | STRCR_1200 | STRCR_1553 | Nucleoside pyrophosphate kinase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.659 |
| awd | guaB | STRCR_1200 | STRCR_0387 | Nucleoside pyrophosphate kinase. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.651 |
| awd | lepA | STRCR_1200 | STRCR_1201 | Nucleoside pyrophosphate kinase. | Putative GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.671 |
| awd | nrdD | STRCR_1200 | STRCR_0301 | Nucleoside pyrophosphate kinase. | Anaerobic ribonucleoside-triphosphate reductase. | 0.914 |
| awd | pyrG | STRCR_1200 | STRCR_0599 | Nucleoside pyrophosphate kinase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.963 |
| awd | rpoB | STRCR_1200 | STRCR_0555 | Nucleoside pyrophosphate kinase. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.620 |
| awd | rpsB | STRCR_1200 | STRCR_0225 | Nucleoside pyrophosphate kinase. | Putative 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.969 |
| fusA | EHI74067.1 | STRCR_0692 | STRCR_0450 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | Phosphoribosylformylglycinamidine synthase. | 0.441 |
| fusA | awd | STRCR_0692 | STRCR_1200 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | Nucleoside pyrophosphate kinase. | 0.514 |
| fusA | guaA | STRCR_0692 | STRCR_1553 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.706 |
| fusA | ileS | STRCR_0692 | STRCR_2198 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | Putative isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.789 |
