Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pbpXPenicillin-binding protein 2X. (750 aa)    
Predicted Functional Partners:
pbp2A
Penicillin-binding protein 2A.
  
 
 0.997
pbp1A
Penicillin-binding protein 1A.
  
 
 0.997
pbp1B
Penicillin-binding protein 1B.
  
 
 0.994
ftsW
Cell division protein, FtsW/RodA/SpoVE family; Belongs to the SEDS family.
 
 0.993
EHI73737.1
Cell division protein, FtsW/RodA/SpoVE family; Belongs to the SEDS family.
 
 0.988
EHI75171.1
Penicillin-binding protein 2B family protein.
  
  
0.981
ftsL
Cell division protein FtsL; Essential cell division protein; Belongs to the FtsL family.
  
 
 0.976
dacA
Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family.
  
 
 0.975
mraY
Putative Phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.970
divIB
Cell division protein DivIB family protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
 
 
 0.958
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
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