nadD protein (Streptococcus criceti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

nadD

Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (210 aa)

Predicted Functional Partners:

EHI75221.1

0.996

cinA

0.968

rsfS

0.856

EHI75442.1

0.838

EHI74137.1

0.817

EHI74174.1

0.761

nadE

0.739

nadK

0.700

pncB

0.699

EHI74326.1

0.699

Your Current Organism:

Streptococcus criceti

NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EHI74137.1	EHI74174.1	STRCR_0893	STRCR_0888	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	GTP-binding protein.	0.403
EHI74137.1	EHI75221.1	STRCR_0893	STRCR_0892	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	HD domain protein.	0.782
EHI74137.1	EHI75442.1	STRCR_0893	STRCR_0890	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	Hypothetical protein.	0.493
EHI74137.1	nadD	STRCR_0893	STRCR_0891	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.817
EHI74137.1	pncB	STRCR_0893	STRCR_0781	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.413
EHI74137.1	rsfS	STRCR_0893	STRCR_0895	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.538
EHI74174.1	EHI74137.1	STRCR_0888	STRCR_0893	GTP-binding protein.	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	0.403
EHI74174.1	EHI75221.1	STRCR_0888	STRCR_0892	GTP-binding protein.	HD domain protein.	0.666
EHI74174.1	EHI75442.1	STRCR_0888	STRCR_0890	GTP-binding protein.	Hypothetical protein.	0.793
EHI74174.1	nadD	STRCR_0888	STRCR_0891	GTP-binding protein.	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.761
EHI74174.1	rsfS	STRCR_0888	STRCR_0895	GTP-binding protein.	Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.902
EHI74326.1	EHI75221.1	STRCR_2079	STRCR_0892	Hydrolase, carbon-nitrogen family.	HD domain protein.	0.566
EHI74326.1	cinA	STRCR_2079	STRCR_0311	Hydrolase, carbon-nitrogen family.	Hypothetical protein; Belongs to the CinA family.	0.653
EHI74326.1	nadD	STRCR_2079	STRCR_0891	Hydrolase, carbon-nitrogen family.	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.699
EHI74326.1	nadE	STRCR_2079	STRCR_0782	Hydrolase, carbon-nitrogen family.	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.	0.668
EHI74326.1	nadK	STRCR_2079	STRCR_1376	Hydrolase, carbon-nitrogen family.	Hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.669
EHI74326.1	rsfS	STRCR_2079	STRCR_0895	Hydrolase, carbon-nitrogen family.	Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.573
EHI75221.1	EHI74137.1	STRCR_0892	STRCR_0893	HD domain protein.	Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.	0.782
EHI75221.1	EHI74174.1	STRCR_0892	STRCR_0888	HD domain protein.	GTP-binding protein.	0.666
EHI75221.1	EHI74326.1	STRCR_0892	STRCR_2079	HD domain protein.	Hydrolase, carbon-nitrogen family.	0.566

page 1 of 4

Server load: low (26%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About