Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
serCPutative phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (364 aa)    
Predicted Functional Partners:
EHI74516.1
D-isomer specific 2-hydroxyacid dehydrogenase family protein.
 
 0.999
serB
Phosphoserine phosphatase SerB.
  
 
 0.978
thrC
Threonine synthase.
   
 0.952
EHI75068.1
Putative cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.930
EHI74278.1
Acetyltransferase, GNAT family.
       0.773
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.773
mnmE
Putative tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
      0.760
EHI74587.1
Hydrolase, haloacid dehalogenase-like family protein.
   
 
 0.738
EHI74067.1
Phosphoribosylformylglycinamidine synthase.
   
  
 0.735
EHI75051.1
Hydrolase, haloacid dehalogenase-like family protein.
   
 
 0.647
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
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