Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EHI75043.1Sensory box sensor histidine kinase. (454 aa)    
Predicted Functional Partners:
EHI73410.1
DNA-binding response regulator.
 0.996
EHI75505.1
Hypothetical protein.
 
 0.926
phoB
Phosphate regulon response regulator PhoB.
 
 0.918
vicX
VicX protein.
 
  
 0.892
EHI75373.1
DNA-binding response regulator.
 
 0.854
EHI74159.1
DNA-binding response regulator.
 0.844
csrR
DNA-binding response regulator CsrR.
 
 0.822
EHI74623.1
Putative transcriptional regulatory protein CiaR.
 0.798
spaR
Subtilin biosynthesis regulatory protein SpaR.
 0.798
EHI74434.1
Hypothetical protein.
 
 0.721
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
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