Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lplALipoate--protein ligase. (329 aa)    
Predicted Functional Partners:
EHI74687.1
Putative TPP-dependent acetoin dehydrogenase complex, E3 component, dihydrolipoyl dehydrogenase.
 
 0.997
EHI74863.1
Putative branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 0.982
acoB
TPP-dependent acetoin dehydrogenase complex, E1 component, beta subunit.
 
  
 0.889
EHI74406.1
Acetoin dehydrogenase, thymine PPi dependent, E1 component, alpha subunit.
 
  
 0.802
fabF
3-oxoacyl-(acyl carrier protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
     
 0.622
EHI75530.1
3-oxoacyl-(acyl carrier protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
     
 0.622
birA
biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
   
  
 0.595
EHI74569.1
Pyridine nucleotide-disulfide oxidoreductase family protein.
 
  
 0.593
ilvE
Branched-chain-amino-acid transaminase.
  
   0.495
EHI73986.1
AtsA/ElaC family protein.
  
    0.484
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.