Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EHI74705.1Transcriptional regulator, AraC family. (294 aa)    
Predicted Functional Partners:
fruA
PTS system, fructose specific IIABC component.
   
 0.886
EHI74958.1
Transcriptional regulator, AraC family.
  
 0.787
EHI73708.1
PTS system mannose-specific EIIAB component family protein.
    
 0.761
EHI73904.1
Putative PTS system mannose-specific EIIAB component.
    
 0.761
glmS
Glutamine--fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.755
EHI75453.1
Hypothetical protein.
 
 
 0.748
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
  0.675
EHI74466.1
Putative UTP--glucose-1-phosphate uridylyltransferase.
    
 0.652
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.638
EHI74688.1
Alcohol dehydrogenase, iron-dependent; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
     
 0.635
Your Current Organism:
Streptococcus criceti
NCBI taxonomy Id: 873449
Other names: S. criceti HS-6, Streptococcus criceti HS-6, Streptococcus criceti str. HS-6, Streptococcus criceti strain HS-6
Server load: low (30%) [HD]